Modification and delivery of enkephalins for pain modulation
Chronic pain negatively affects patient's quality of life and poses a significant economic
burden. First line pharmaceutical treatment of chronic pain, including NSAIDs or …
burden. First line pharmaceutical treatment of chronic pain, including NSAIDs or …
Analgesic Peptides: From Natural Diversity to Rational Design
K Gach-Janczak, M Biernat, M Kuczer… - Molecules, 2024 - mdpi.com
Pain affects one-third of the global population and is a significant public health issue. The
use of opioid drugs, which are the strongest painkillers, is associated with several side …
use of opioid drugs, which are the strongest painkillers, is associated with several side …
Special Issue “Peptides for Health Benefits 2021”
C Martínez-Villaluenga… - International Journal of …, 2024 - mdpi.com
In recent years, non-communicable diseases (NCDs) have increased in prevalence in our
society and have become a serious burden of disease worldwide. More than 50% of all …
society and have become a serious burden of disease worldwide. More than 50% of all …
BNT12, a novel hybrid peptide of opioid and neurotensin pharmacophores, produces potent central antinociception with limited side effects
S Wang, Y Zhang, X Liu, X Guo, X Wang… - European Journal of …, 2024 - Elsevier
The development of multitarget opioid drugs has emerged as an attractive approach for
innovative pain management with reduced side effects. In the present study, a novel hybrid …
innovative pain management with reduced side effects. In the present study, a novel hybrid …
The influence of a synthetic growth hormone‐releasing hormone analogue G11 and opioid peptide biphalin on selected fibroblasts parameters relevant to wound …
P Redkiewicz, J Dyniewicz, E Witkowska… - Journal of Peptide …, 2023 - Wiley Online Library
The treatment of hard‐to‐heal chronic wounds is still a major medical problem and an
economic and social burden. In this work, we examine the proregenerative potential of two …
economic and social burden. In this work, we examine the proregenerative potential of two …
Development of a novel Enkephalin-like peptide with pain-relieving and antidepressant-like effects
L Hohenwarter - 2023 - open.library.ubc.ca
Chronic pain affects approximately 20% of Canadians and is a global healthcare burden
with limited treatment options. The high incidence of comorbid chronic pain and depression …
with limited treatment options. The high incidence of comorbid chronic pain and depression …