Longitudinal x-ray based lung function measurement for monitoring Nintedanib treatment response in a mouse model of lung fibrosis
A Khan, MA Markus, A Svetlove, S Hülsmann… - Scientific Reports, 2023 - nature.com
Lung fibrosis (LF) is a chronic progressive, incurable, and debilitating condition of the lung,
which is associated with different lung disease. Treatment options are still sparse …
which is associated with different lung disease. Treatment options are still sparse …
European Respiratory Society International Congress, Milan, 2023: Highlights from the Assembly 1–Respiratory clinical care and physiology
A Gonsard, E Mekov, S Barron… - ERJ Open …, 2024 - Eur Respiratory Soc
It is a challenge to keep abreast of all the clinical and scientific advances in the field of
respiratory medicine. This article contains an overview of laboratory-based science, clinical …
respiratory medicine. This article contains an overview of laboratory-based science, clinical …
Micro-CT-assisted identification of the optimal time-window for antifibrotic treatment in a bleomycin mouse model of long-lasting pulmonary fibrosis
M Buccardi, A Grandi, E Ferrini, D Buseghin… - Scientific Reports, 2024 - nature.com
Abstract Idiopathic Pulmonary Fibrosis (IPF) is a debilitating and fatal lung disease
characterized by the excessive formation of scar tissue and decline of lung function. Despite …
characterized by the excessive formation of scar tissue and decline of lung function. Despite …
Multiphase micro-computed tomography reconstructions provide dynamic respiratory function in a mouse lung fibrosis model
F Pennati, S Belenkov, M Buccardi, E Ferrini… - Iscience, 2024 - cell.com
Micro-computed tomography derived functional biomarkers used in lung disease research
can significantly complement end-stage histomorphometric measures while also allowing for …
can significantly complement end-stage histomorphometric measures while also allowing for …
Stacking learning based on micro-CT radiomics for outcome prediction in the early-stage of silica-induced pulmonary fibrosis model
H Wang, Q Jia, Y Wang, W Xue, Q Jiang, F Ning… - Heliyon, 2024 - cell.com
Silicosis is a progressive pulmonary fibrosis disease caused by long-term inhalation of
silica. The early diagnosis and timely implementation of intervention measures are crucial in …
silica. The early diagnosis and timely implementation of intervention measures are crucial in …
In vivo low-dose phase-contrast CT for quantification of functional and anatomical alterations in lungs of an experimental allergic airway disease mouse model
Introduction Synchrotron-based propagation-based imaging (PBI) is ideally suited for lung
imaging and has successfully been applied in a variety of in vivo small animal studies …
imaging and has successfully been applied in a variety of in vivo small animal studies …
ERS International Congress 2023: highlights from the Respiratory Clinical Care and Physiology Assembly
A Gonsard, E Mekov, S Barron… - ERJ Open …, 2024 - Eur Respiratory Soc
It is a challenge to keep abreast of all the clinical and scientific advances in the field of
respiratory medicine. This article contains an overview of laboratory-based science, clinical …
respiratory medicine. This article contains an overview of laboratory-based science, clinical …
Radioproteomics stratifies molecular response to antifibrotic treatment in pulmonary fibrosis
D Lauer, CY Magnin, L Kolly, H Wang, M Brunner… - bioRxiv, 2024 - biorxiv.org
Antifibrotic therapy with nintedanib is the clinical mainstay in the treatment of progressive
fibrosing interstitial lung disease (ILD). High-dimensional medical image analysis, known as …
fibrosing interstitial lung disease (ILD). High-dimensional medical image analysis, known as …
Monitoring the response to Nintedanib treatment in a mouse model of lung fibrosis using longitudinal X-ray based lung function measurement
Background: Idiopathic pulmonary fibrosis (IPF) is a chronic progressive, incurable, and
debilitating fibrotic disease. Nintedanib–an oral tyrosine kinase inhibitor–significantly slows …
debilitating fibrotic disease. Nintedanib–an oral tyrosine kinase inhibitor–significantly slows …