Type 1 diabetes (T1D) is a chronic autoimmune disease leading to immune-mediated
destruction of pancreatic beta cells, resulting in the need for insulin therapy. The incidence …

Vitamin D may have multiple effects on the nervous system and its deficiency can represent
a possible risk factor for the development of many neurological diseases. Recent studies are …

Vitamin D has received increased attention recently for its pleiotropic actions on many
chronic diseases. The importance of vitamin D on the regulation of cells of the immune …

It is widely known that vitamin D receptors have been found in neurons and glial cells, and
their highest expression is in the hippocampus, hypothalamus, thalamus and subcortical …

Immunomodulatory actions of vitamin D have been recognised for over a quarter of a
century, but it is only in the last few years that the significance of this to normal human …

Introduction Rheumatoid arthritis (RA) is a chronic systemic disease characterized by
articular involvement and extra-articular manifestations. The incidence and prevalence of …

Calcitriol, or 1, 25-dihydroxyvitamin D3 (1, 25 (OH) 2D3) is a well-known endocrine regulator
of calcium homeostasis. More recently, local calcitriol production by immune cells was …

Vitamin D deficiency has been correlated with increased rates of infection. Since the early
19th century, both environmental (ie, sunlight) and dietary sources (cod liver) of vitamin D …

Multiple sclerosis (MS) is a chronic inflammatory demyelinating and neurodegenerative
disease of the central nervous system (CNS). In recent years, vitamin D has gained …

Abstract Knowledge about the ability of vitamin D to function outside its established role in
skeletal homeostasis is not a new phenomenon. Nonclassical immunomodulatory and …