Gut microbiome-mediated mechanisms for reducing cholesterol levels: implications for ameliorating cardiovascular disease
Cardiovascular disease (CVD) is a health problem worldwide, and elevated cholesterol
levels are a key risk factor for the disease. Dysbiotic gut microbiota has been shown to be …
levels are a key risk factor for the disease. Dysbiotic gut microbiota has been shown to be …
[HTML][HTML] Foam cells in atherosclerosis: novel insights into its origins, consequences, and molecular mechanisms
Y Gui, H Zheng, RY Cao - Frontiers in Cardiovascular Medicine, 2022 - frontiersin.org
Foam cells play a vital role in the initiation and development of atherosclerosis. This review
aims to summarize the novel insights into the origins, consequences, and molecular …
aims to summarize the novel insights into the origins, consequences, and molecular …
Verification of ferroptosis and pyroptosis and identification of PTGS2 as the hub gene in human coronary artery atherosclerosis
Y Zhou, H Zhou, L Hua, C Hou, Q Jia, J Chen… - Free Radical Biology …, 2021 - Elsevier
Ferroptosis and pyroptosis have not been fully studied in atherosclerosis. We aimed to
investigate the expression of ferroptosis-related and pyroptosis-related proteins in human …
investigate the expression of ferroptosis-related and pyroptosis-related proteins in human …
[HTML][HTML] Triacylglycerol uptake and handling by macrophages: From fatty acids to lipoproteins
Macrophages are essential innate immune cells and form our first line of immune defense.
Also known as professional phagocytes, macrophages interact and take up various …
Also known as professional phagocytes, macrophages interact and take up various …
[HTML][HTML] Protective effects of oleic acid and polyphenols in extra virgin olive oil on cardiovascular diseases
Y Lu, J Zhao, Q Xin, R Yuan, Y Miao, M Yang… - Food Science and …, 2024 - Elsevier
The Mediterranean diet has long been recognized as one of the most effective ways to
prevent and improve cardiovascular disease. Extra virgin olive oil (EVOO) is the typical …
prevent and improve cardiovascular disease. Extra virgin olive oil (EVOO) is the typical …
Endothelial function and endothelial progenitor cells in systemic lupus erythematosus
The observations that traditional cardiovascular disease (CVD) risk factors fail to fully
account for the excessive cardiovascular mortality in patients with systemic lupus …
account for the excessive cardiovascular mortality in patients with systemic lupus …
RNA modifications in cardiovascular diseases, the potential therapeutic targets
Y Wu, S Zhan, Y Xu, X Gao - Life Sciences, 2021 - Elsevier
More than one hundred RNA modifications decorate the chemical and topological properties
of these ribose nucleotides, thereby executing their biological functions through post …
of these ribose nucleotides, thereby executing their biological functions through post …
[HTML][HTML] Asprosin inhibits macrophage lipid accumulation and reduces atherosclerotic burden by up-regulating ABCA1 and ABCG1 expression via the p38/Elk-1 …
J Zou, C Xu, ZW Zhao, SH Yin, G Wang - Journal of Translational …, 2022 - Springer
Background Asprosin, a newly discovered adipokine, is a C-terminal cleavage product of
profibrillin. Asprosin has been reported to participate in lipid metabolism and cardiovascular …
profibrillin. Asprosin has been reported to participate in lipid metabolism and cardiovascular …
Trimethylamine N-oxide promotes oxidative stress and lipid accumulation in macrophage foam cells via the Nrf2/ABCA1 pathway
ZS Luo, XC Yu, C Wang, HY Zhao, X Wang… - Journal of physiology …, 2024 - Springer
Recently, trimethylamine N-oxide (TMAO) has been considered a risk factor for
cardiovascular disease and has a proatherogenic effect. Many studies have found that …
cardiovascular disease and has a proatherogenic effect. Many studies have found that …
NLRP3 inflammasome in atherosclerosis: putting out the fire of inflammation
BZ Shao, HY Xu, YC Zhao, XR Zheng, F Wang… - Inflammation, 2023 - Springer
Atherosclerosis (AS) is a chronic inflammatory disease with thickening or hardening of the
arteries, which led to the built-up of plaques in the inner lining of an artery. Among all the …
arteries, which led to the built-up of plaques in the inner lining of an artery. Among all the …