Blood-Brain Barrier (BBB) disruption is an important pathophysiological process of acute
ischemic stroke (AIS), resulting in devastating malignant brain edema and hemorrhagic …

Pericytes, as a key cellular part of the blood-brain barrier, play an important role in the
maintenance of brain neurovascular unit. These cells participate in brain homeostasis by …

Hepatocellular carcinoma (HCC) is the third foremost cause of cancer-related deaths. HCC
has a very bad prognosis because it is asymptomatic in the early stages, resulting in a late …

A central characteristic of many types of cancer is altered energy metabolism processes
such as enhanced glucose uptake and glycolysis and decreased oxidative metabolism. The …

Cerebral ischemia induces massive mitochondrial damage, leading to neuronal death. The
elimination of damaged mitochondria via mitophagy is critical for neuroprotection. Here we …

Signal transducer and activator of transcription 3 (STAT3) functions as a major molecular
switch that plays an important role in the communication between cytokines and kinases. In …

Idiopathic pulmonary fibrosis is a fatal lung disorder in which the etiology and pathogenesis
are still unobvious. Effective treatments are urgently needed considering that lung …

Chloroquines are 4‐aminoquinoline‐based drugs mainly used to treat malaria. At
pharmacological concentrations, they have significant effects on tissue homeostasis …

The current treatment options for ischemic stroke aim to achieve reperfusion but are time
critical. Novel therapeutic approaches that can be given beyond the limited time window of 3 …

Oxygen supply for ischemic brain tissue during stroke is critical to neuroprotection. Remote
ischemic conditioning (RIC) treatment is effective for stroke. However, it is not known …