Stroke prevention in patients with atrial fibrillation (AF) is one pillar of the management of
this common arrhythmia. Substantial advances in the epidemiology and associated …

The first international guidance on antithrombotic therapy in the elderly came from the
European Society of Cardiology Working Group on Thrombosis in 2015. This same group …

Aims The respective roles of oral anticoagulation or antiplatelet therapy following
transcatheter aortic valve implantation (TAVI) remain debated. ATLANTIS is an international …

Background: It is unknown whether the direct oral anticoagulant edoxaban can reduce
leaflet thrombosis and the accompanying cerebral thromboembolic risk after transcatheter …

Since the first groundbreaking procedure in 2002, transcatheter aortic valve implantation
(TAVI) has revolutionized the management of aortic stenosis (AS). Through striking …

Transcatheter aortic valve replacement (TAVR) has gained over time a major reduction in
procedural complications. Despite this, clinically relevant bleeding still occurs in a non …

Background Subclinical obstructive valve thrombosis after transcatheter aortic valve
replacement (TAVR) is of uncertain frequency and clinical impact. Objectives The aim of this …

In the recent years, there has been significant transformation in the management of valvular
heart disease (VHD), as a result of new minimally invasive technologies, such as the …

Antiplatelet therapy plays a crucial role in a number of cardiovascular disorders. We
currently have a range of antiplatelet agents in our armamentarium. In this review, we aim to …

The impact of sex on pathophysiological processes, clinical presentation, treatment options,
as well as outcomes of degenerative aortic stenosis remain poorly understood. Female …