Statin use for the primary prevention of cardiovascular disease in adults: updated evidence report and systematic review for the US Preventive Services Task Force

R Chou, A Cantor, T Dana, J Wagner, AY Ahmed, R Fu… - Jama, 2022 - jamanetwork.com
Importance A 2016 review for the US Preventive Services Task Force (USPSTF) found use
of statins for primary prevention of cardiovascular disease (CVD) was associated with …

Statins for prevention of cardiovascular disease in adults: evidence report and systematic review for the US Preventive Services Task Force

R Chou, T Dana, I Blazina, M Daeges, TL Jeanne - Jama, 2016 - jamanetwork.com
Importance Cardiovascular disease (CVD), the leading cause of mortality and morbidity in
the United States, may be potentially preventable with statin therapy. Objective To …

The evolving future of PCSK9 inhibitors

RS Rosenson, RA Hegele, S Fazio… - Journal of the American …, 2018 - jacc.org
Variants in proprotein convertase subtilisin/kexin type 9 (PCSK9) provide insights into
mechanisms regulating low-density lipoprotein (LDL) levels. Human monoclonal antibodies …

Lipid management in patients with endocrine disorders: an endocrine society clinical practice guideline

CB Newman, MJ Blaha, JB Boord… - The Journal of …, 2020 - academic.oup.com
Objective This guideline will provide the practicing endocrinologist with an approach to the
assessment and treatment of dyslipidemia in patients with endocrine diseases, with the …

Intensive low-density lipoprotein cholesterol lowering in cardiovascular disease prevention: opportunities and challenges

C Packard, MJ Chapman, M Sibartie, U Laufs… - Heart, 2021 - heart.bmj.com
Elevated levels of low-density lipoprotein cholesterol (LDL-C) are associated with increased
risk of coronary heart disease and stroke. Guidelines for the management of dyslipidaemia …

Risk of incident diabetes among patients treated with statins: population based study

AA Carter, T Gomes, X Camacho, DN Juurlink… - Bmj, 2013 - bmj.com
Objective To examine the risk of new onset diabetes among patients treated with different
HMG-CoA reductase inhibitors (statins). Design Population based cohort study with time to …

[HTML][HTML] Garlic lowers blood pressure in hypertensive individuals, regulates serum cholesterol, and stimulates immunity: an updated meta-analysis and review

K Ried - The Journal of nutrition, 2016 - Elsevier
Background: Garlic has been shown to have cardiovascular protective and
immunomodulatory properties. Objectives: We updated a previous meta-analysis on the …

Long-term safety and efficacy of lowering low-density lipoprotein cholesterol with statin therapy: 20-year follow-up of West of Scotland Coronary Prevention Study

I Ford, H Murray, C McCowan, CJ Packard - Circulation, 2016 - Am Heart Assoc
Background—Extended follow-up of statin-based low-density lipoprotein cholesterol
lowering trials improves the understanding of statin safety and efficacy. Examining …

Meta-analysis of impact of different types and doses of statins on new-onset diabetes mellitus

EP Navarese, A Buffon, F Andreotti, M Kozinski… - The American journal of …, 2013 - Elsevier
Recent reports indicate that statins are associated with an increased risk for new-onset
diabetes mellitus (DM) compared with placebo and that this relation is dose dependent. The …

[HTML][HTML] Obesity and dyslipidemia

KR Feingold - 2015 - europepmc.org
Abnormalities in lipid metabolism are very commonly observed in patients who are obese.
Approximately 60-70% of patients with obesity are dyslipidemic. The lipid abnormalities in …