[HTML][HTML] Advances in single-cell RNA sequencing and its applications in cancer research

D Huang, N Ma, X Li, Y Gou, Y Duan, B Liu… - Journal of hematology & …, 2023 - Springer
Cancers are a group of heterogeneous diseases characterized by the acquisition of
functional capabilities during the transition from a normal to a neoplastic state. Powerful …

[HTML][HTML] Understanding the Immunopathology of HTLV-1-Associated Adult T-Cell Leukemia/Lymphoma: A Comprehensive Review

S Nakahata, D Enriquez-Vera, MI Jahan, K Sugata… - Biomolecules, 2023 - mdpi.com
Human T-cell leukemia virus type-1 (HTLV-1) causes adult T-cell leukemia/lymphoma (ATL).
HTLV-1 carriers have a lifelong asymptomatic balance between infected cells and host …

Global patterns of non‐Hodgkin lymphoma in 2020

A Mafra, M Laversanne… - … journal of cancer, 2022 - Wiley Online Library
We evaluated the global patterns of non‐Hodgkin lymphoma (NHL) in 2020 using the
estimates of NHL incidence and mortality in 185 countries that are part of the GLOBOCAN …

HNSPPI: a hybrid computational model combing network and sequence information for predicting protein–protein interaction

S Xie, X Xie, X Zhao, F Liu, Y Wang… - Briefings in …, 2023 - academic.oup.com
Most life activities in organisms are regulated through protein complexes, which are mainly
controlled via Protein–Protein Interactions (PPIs). Discovering new interactions between …

[HTML][HTML] Identification and characterization of a novel enhancer in the HTLV-1 proviral genome

M Matsuo, T Ueno, K Monde, K Sugata… - Nature …, 2022 - nature.com
Human T-cell leukemia virus type 1 (HTLV-1) is an oncogenic virus with constantly active
antisense transcription from the proviral genome. Here, Matsuo et al. perform proviral DNA …

Integrated molecular and immunological features of human T-lymphotropic virus type 1 infection and disease progression to adult T-cell leukaemia or lymphoma

JS O'Donnell, SK Hunt, KJ Chappell - The Lancet Haematology, 2023 - thelancet.com
The human T-lymphotropic virus type 1 (HTLV-1) retrovirus infects 10–20 million people
globally, with endemic regions in southwestern Japan, the Caribbean basin, Africa, and …

[HTML][HTML] Deciphering the roles of myeloid derived suppressor cells in viral oncogenesis

A Glover, Z Zhang, C Shannon-Lowe - Frontiers in immunology, 2023 - frontiersin.org
Myeloid derived suppressor cells (MDSCs) are a heterogenous population of myeloid cells
derived from monocyte and granulocyte precursors. They are pathologically expanded in …

Viral, genetic, and immune factors in the oncogenesis of adult T-cell leukemia/lymphoma

J Yasunaga - International Journal of Hematology, 2023 - Springer
Adult T-cell leukemia/lymphoma (ATL) is a malignancy of mature CD4+ T cells induced by
human T-cell leukemia virus type I (HTLV-1). HTLV-1 maintains life-long infection in the …

HTLV‐1 persistent infection and ATLL oncogenesis

X Zuo, R Zhou, S Yang, G Ma - Journal of Medical Virology, 2023 - Wiley Online Library
Human T‐cell leukemia virus type 1 (HTLV‐1) was discovered in the 1980s, but it is
estimated to have been infecting humans for more than ten thousand years. 1 With over 90 …

[HTML][HTML] The endogenous HBZ interactome in ATL leukemic cells reveals an unprecedented complexity of host interacting partners involved in RNA splicing

M Shallak, T Alberio, M Fasano, M Monti… - Frontiers in …, 2022 - frontiersin.org
Adult T-cell leukemia/lymphoma (ATL) is a T-cell lymphoproliferative neoplasm caused by
the human T-cell leukemia virus type 1 (HTLV-1). Two viral proteins, Tax-1 and HBZ play …