Multimodal strategies to improve surgical outcome

H Kehlet, DW Wilmore - The American journal of surgery, 2002 - Elsevier
Objective: To evaluate the effect of modifying perioperative care in noncardiac surgical
patients on morbidity, mortality, and other outcome measures. Background: New …

Anaesthesia, surgery, and challenges in postoperative recovery

H Kehlet, JB Dahl - The Lancet, 2003 - thelancet.com
Surgical injury can be followed by pain, nausea, vomiting and ileus, stress-induced
catabolism, impaired pulmonary function, increased cardiac demands, and risk of …

A qualitative and quantitative systematic review of preemptive analgesia for postoperative pain relief: the role of timing of analgesia

S Møiniche, H Kehlet, JB Dahl - … Journal of the American Society of …, 2002 - pubs.asahq.org
THE concept of preemptive analgesia to reduce the magnitude and duration of
postoperative pain was paved in 1983 by Woolf, 1 who showed evidence for a central …

The transversus abdominis plane block provides effective postoperative analgesia in patients undergoing total abdominal hysterectomy

J Carney, JG McDonnell, A Ochana… - Anesthesia & …, 2008 - journals.lww.com
BACKGROUND: Patients undergoing total abdominal hysterectomy suffer significant
postoperative pain. The transversus abdominis plane (TAP) block is a recently described …

[HTML][HTML] Efficacy of continuous wound catheters delivering local anesthetic for postoperative analgesia: a quantitative and qualitative systematic review of randomized …

SS Liu, JM Richman, RC Thirlby… - Database of Abstracts of …, 2006 - ncbi.nlm.nih.gov
This review evaluated the efficacy of continuous wound catheters in delivering local
anaesthetic in postoperative analgesia. Continuous wound catheters were found to improve …

Analgesic efficacy of ultrasound-guided transversus abdominis plane block in patients undergoing open appendicectomy

G Niraj, A Searle, M Mathews, V Misra… - British journal of …, 2009 - academic.oup.com
Background Transversus abdominis plane (TAP) block is a new regional anaesthetic
technique that blocks abdominal neural afferents by introducing local anaesthetic into the …

A randomized, double-blind, dose-ranging study comparing wound infiltration of DepoFoam bupivacaine, an extended-release liposomal bupivacaine, to bupivacaine …

K Bramlett, E Onel, ER Viscusi, K Jones - The Knee, 2012 - Elsevier
INTRODUCTION: DepoFoam bupivacaine is a novel liposomal formulation of bupivacaine
designed to provide prolonged postsurgical analgesia. This dose-ranging study evaluated …

A qualitative systematic review of the role of N-methyl-D-aspartate receptor antagonists in preventive analgesia

CJL McCartney, A Sinha, J Katz - Anesthesia & Analgesia, 2004 - journals.lww.com
IMPLICATIONS: We evaluated, in a qualitative systematic review, the effect of N-methyl d-
aspartate antagonists on reducing postoperative pain and analgesic consumption beyond …

Comparison between ultrasound-guided transversus abdominis plane and conventional ilioinguinal/iliohypogastric nerve blocks for day-case open inguinal hernia …

C Aveline, H Le Hetet, A Le Roux… - British journal of …, 2011 - academic.oup.com
Background Transversus abdominis plane (TAP) block has been reported to provide
effective analgesia after lower abdominal surgery, but there are few data comparing …

Pharmacokinetic profile of liposome bupivacaine injection following a single administration at the surgical site

DD Hu, E Onel, N Singla, WG Kramer… - Clinical drug …, 2013 - Springer
Local anaesthetics are often used as part of multimodal pain management techniques to
manage postsurgical pain and lessen the need for opioid analgesics; however, the duration …