Hypoxic-ischemic encephalopathy (HIE) is a major cause of neurological sequelae in (near-
) term newborns. Despite the use of therapeutic hypothermia, a significant number of …

Introduction Perinatal asphyxia (PA) still causes significant morbidity and mortality.
Therapeutic hypothermia (TH) is the only effective therapy for neonates with moderate to …

Objective To assess the evolution of neonatal brain injury noted on magnetic resonance
imaging (MRI), develop a score to assess brain injury on 3-month MRI, and determine the …

Abstract Introduction: Erythropoietin (Epo) is a putative neuroprotective therapy that did not
improve overall outcomes in a phase 3 randomized controlled trial for neonates with …

Introduction: The brain magnetic resonance imaging (MRI) result is a major predictor for the
outcome of term infants with perinatal asphyxia who underwent therapeutic hypothermia. In …

Neonates with neonatal encephalopathy (NE) often present with multi-organ dysfunction that
requires multidisciplinary specialized management. Care of the neonate with NE is thus …

Objective To test feasibility and safety of administering sildenafil in neonates with neonatal
encephalopathy (NE), developing brain injury despite therapeutic hypothermia (TH). Study …

Background Therapeutic hypothermia (TH) is the gold-standard treatment for moderate and
severe neonatal encephalopathy (NE). Care during TH has implications for long-term …

Background MRI is the gold standard test to define brain injury in infants with neonatal
encephalopathy (NE). As imaging findings evolve considerably over the first week, early …

Background: Magnetic resonance imaging (MRI) including diffusion-weighted imaging
within seven days after birth is widely used to obtain prognostic information in neonatal …