Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by a failure of
spontaneous resolution of inflammation. Although the pro-inflammatory cytokines and …

Acute inflammation is a physiological response to injury or infection, with a cascade of steps
that ultimately lead to the recruitment of immune cells to clear invading pathogens and heal …

Aging is characterized by a morpho-functional adaptation, variably affecting major
physiological systems, depending on a complex interaction between genetic, environmental …

Sarcopenia, obesity and their coexistence, obese sarcopenia (OBSP) as well as
atherosclerosis-related cardio-vascular diseases (ACVDs), including chronic heart failure …

Lipid metabolism plays a major role in the regulation of the immune system. Exogenous
(dietary and microbial-derived) and endogenous (non-microbial-derived) lipids play a direct …

Multiple sclerosis (MS) is a frequent autoimmune demyelinating disease of the central
nervous system (CNS). There are three clinical forms described: relapsing-remitting multiple …

Docosahexaenoic acid (C22: 6 n-3, DHA) is the precursor of specialized pro-resolving lipid
mediators (SPMs), such as resolvin, protectin, and maresin families which have been …

Chronic pain (CP) is a severe clinical entity with devastating physical and emotional
consequences for patients, which can occur in a myriad of diseases. Often, conventional …

Background Leukocyte‐directed biosynthesis of specialized proresolving mediators (SPMs)
orchestrates physiological inflammation after myocardial infarction. Deficiency of SPMs …

Alterations in lipid metabolism have the potential to be markers as well as drivers of
pathobiology of acute critical illness. Here, we took advantage of the temporal precision …