The oxytocin receptor: from intracellular signaling to behavior

B Jurek, ID Neumann - Physiological reviews, 2018 - journals.physiology.org
The many facets of the oxytocin (OXT) system of the brain and periphery elicited nearly
25,000 publications since 1930 (see, as listed in PubMed), which revealed central roles for …

Drug addiction: hyperkatifeia/negative reinforcement as a framework for medications development

GF Koob - Pharmacological Reviews, 2021 - ASPET
Compulsive drug seeking that is associated with addiction is hypothesized to follow a
heuristic framework that involves three stages (binge/intoxication, withdrawal/negative affect …

The oxytocin receptor system: structure, function, and regulation

G Gimpl, F Fahrenholz - Physiological reviews, 2001 - journals.physiology.org
The neurohypophysial peptide oxytocin (OT) and OT-like hormones facilitate reproduction in
all vertebrates at several levels. The major site of OT gene expression is the magnocellular …

Neuroendocrine perspectives on social attachment and love

CS Carter - Psychoneuroendocrinology, 1998 - Elsevier
The purpose of this paper is to review existing behavioral and neuroendocrine perspectives
on social attachment and love. Both love and social attachments function to facilitate …

The neurobiology of pair bonding

LJ Young, Z Wang - Nature neuroscience, 2004 - nature.com
A neurobiological model for pair-bond formation has emerged from studies in monogamous
rodents. The neuropeptides oxytocin and vasopressin contribute to the processing of social …

Coregulation, dysregulation, self-regulation: An integrative analysis and empirical agenda for understanding adult attachment, separation, loss, and recovery

DA Sbarra, C Hazan - Personality and Social Psychology …, 2008 - journals.sagepub.com
An integrative framework is proposed for understanding how multiple biological and
psychological systems are regulated in the context of adult attachment relationships …

Is social attachment an addictive disorder?

TR Insel - Physiology & behavior, 2003 - Elsevier
There is a considerable literature on the neurobiology of reward, based largely on studies of
addiction or substance abuse. This review considers the possibility that the neural circuits …

Prosocial effects of oxytocin and clinical evidence for its therapeutic potential

N Striepens, KM Kendrick, W Maier… - Frontiers in …, 2011 - Elsevier
There has been unprecedented interest in the prosocial effects of the neuropeptide oxytocin
in humans over the last decade. A range of studies has demonstrated correlations between …

The behavioral, anatomical and pharmacological parallels between social attachment, love and addiction

JP Burkett, LJ Young - Psychopharmacology, 2012 - Springer
Rationale Love has long been referred to as an addiction in literature and poetry. Scientists
have often made comparisons between social attachment processes and drug addiction …

Developmental consequences of oxytocin

CS Carter - Physiology & behavior, 2003 - Elsevier
This paper examines the developmental effects of the mammalian neuropeptide, oxytocin
(OT). In adults, OT is the most abundant neuropeptide in the hypothalamus and serves …