Concussion as a multi-scale complex system: an interdisciplinary synthesis of current knowledge
Traumatic brain injury (TBI) has been called “the most complicated disease of the most
complex organ of the body” and is an increasingly high-profile public health issue. Many …
complex organ of the body” and is an increasingly high-profile public health issue. Many …
White matter and cognition in traumatic brain injury
CM Filley, JP Kelly - Journal of Alzheimer's Disease, 2018 - content.iospress.com
Traumatic brain injury (TBI) is a leading cause of disability and produces a wide range of
cognitive, emotional, and physical consequences. The impact of TBI on cognition is among …
cognitive, emotional, and physical consequences. The impact of TBI on cognition is among …
The evolution of white matter microstructural changes after mild traumatic brain injury: a longitudinal DTI and NODDI study
Neuroimaging biomarkers that can detect white matter (WM) pathology after mild traumatic
brain injury (mTBI) and predict long-term outcome are needed to improve care and develop …
brain injury (mTBI) and predict long-term outcome are needed to improve care and develop …
Diffusion tensor imaging reveals elevated diffusivity of white matter microstructure that is independently associated with long-term outcome after mild traumatic brain …
EM Palacios, EL Yuh, CL Mac Donald… - Journal of …, 2022 - liebertpub.com
Diffusion tensor imaging (DTI) literature on single-center studies contains conflicting results
regarding acute effects of mild traumatic brain injury (mTBI) on white matter (WM) …
regarding acute effects of mild traumatic brain injury (mTBI) on white matter (WM) …
The dynamics of concussion: mapping pathophysiology, persistence, and recovery with causal-loop diagramming
Despite increasing public awareness and a growing body of literature on the subject of
concussion, or mild traumatic brain injury, an urgent need still exists for reliable diagnostic …
concussion, or mild traumatic brain injury, an urgent need still exists for reliable diagnostic …
Early versus late profiles of inflammatory cytokines after mild traumatic brain injury and their association with neuropsychological outcomes
A Vedantam, J Brennan, HS Levin… - Journal of …, 2021 - liebertpub.com
Despite pre-clinical evidence for the role of inflammation in traumatic brain injury (TBI), there
is limited data on inflammatory biomarkers in mild TBI (mTBI). In this study, we describe the …
is limited data on inflammatory biomarkers in mild TBI (mTBI). In this study, we describe the …
A pre-existing Toxoplasma gondii infection exacerbates the pathophysiological response and extent of brain damage after traumatic brain injury in mice
Traumatic brain injury (TBI) is a key contributor to global morbidity that lacks effective
treatments. Microbial infections are common in TBI patients, and their presence could modify …
treatments. Microbial infections are common in TBI patients, and their presence could modify …
Current trends in biomarker discovery and analysis tools for traumatic brain injury
BI Martinez, SE Stabenfeldt - Journal of biological engineering, 2019 - Springer
Traumatic brain injury (TBI) affects 1.7 million people in the United States each year, causing
lifelong functional deficits in cognition and behavior. The complex pathophysiology of neural …
lifelong functional deficits in cognition and behavior. The complex pathophysiology of neural …
Brain correlates of subjective cognitive complaints in COVID-19 survivors: A multimodal magnetic resonance imaging study
Cognitive impairment represents a leading residual symptom of COVID-19 infection, which
lasts for months after the virus clearance. Up-to-date scientific reports documented a wide …
lasts for months after the virus clearance. Up-to-date scientific reports documented a wide …
White matter alterations in military service members with remote mild traumatic brain injury
S Kim, J Ollinger, C Song, S Raiciulescu… - JAMA network …, 2024 - jamanetwork.com
Importance Mild traumatic brain injury (mTBI) is the signature injury experienced by military
service members and is associated with poor neuropsychiatric outcomes. Yet, there is a lack …
service members and is associated with poor neuropsychiatric outcomes. Yet, there is a lack …