Asthma is a chronic inflammatory airway disease associated with type 2 cytokines
interleukin-4 (IL-4), IL-5, and IL-13, which promote airway eosinophilia, mucus …

Human aging is a multifactorial phenomenon that affects numerous organ systems and
cellular processes, with the immune system being one of the most dysregulated …

Persistent inflammation within the respiratory tract underlies the pathogenesis of numerous
chronic pulmonary diseases including chronic obstructive pulmonary disease, asthma and …

The methodology for EPOS2012 has been the same as for the other two productions.
Leaders in the field were invited to critically appraise the literature and write a report on a …

Improvements in our knowledge of the gut microbiota have broadened our vision of the
microbes associated with the intestine. These microbes are essential actors and protectors …

Asthma is a global health problem affecting around 300 million individuals of all ages, ethnic
groups and countries. It is estimated that around 250,000 people die prematurely each year …

Allergic disorders, such as anaphylaxis, hay fever, eczema and asthma, now afflict roughly
25% of people in the developed world. In allergic subjects, persistent or repetitive exposure …

Barrier epithelial cells and airway dendritic cells (DCs) make up the first line of defense
against inhaled substances such as house dust mite (HDM) allergen and endotoxin …

House dust mite (HDM) is one of the most common allergens worldwide. In this study, we
have addressed the involvement of IL-1 in the interaction between HDM and the innate …

Background Air pollutants are important factors that contribute to the development and
exacerbation of asthma, but experimental evidence still needs to be collected and the …