Prognostic and predictive biomarkers for immunotherapy in advanced renal cell carcinoma
M Rosellini, A Marchetti, V Mollica, A Rizzo… - Nature Reviews …, 2023 - nature.com
The therapeutic algorithm of renal cell carcinoma has been revolutionized by the approval of
immunotherapy agents by regulatory agencies. However, objective and durable responses …
immunotherapy agents by regulatory agencies. However, objective and durable responses …
A literature survey of all volatiles from healthy human breath and bodily fluids: the human volatilome
N Drabińska, C Flynn, N Ratcliffe… - Journal of breath …, 2021 - iopscience.iop.org
This paper comprises an updated version of the 2014 review which reported 1846 volatile
organic compounds (VOCs) identified from healthy humans. In total over 900 additional …
organic compounds (VOCs) identified from healthy humans. In total over 900 additional …
[HTML][HTML] Volatile organic compounds in exhaled breath as fingerprints of lung cancer, asthma and COPD
IA Ratiu, T Ligor, V Bocos-Bintintan… - Journal of clinical …, 2020 - mdpi.com
Lung cancer, chronic obstructive pulmonary disease (COPD) and asthma are inflammatory
diseases that have risen worldwide, posing a major public health issue, encompassing not …
diseases that have risen worldwide, posing a major public health issue, encompassing not …
[HTML][HTML] Breath analysis: a promising tool for disease diagnosis—the role of sensors
M Kaloumenou, E Skotadis, N Lagopati… - Sensors, 2022 - mdpi.com
Early-stage disease diagnosis is of particular importance for effective patient identification as
well as their treatment. Lack of patient compliance for the existing diagnostic methods …
well as their treatment. Lack of patient compliance for the existing diagnostic methods …
[HTML][HTML] Accuracy and methodologic challenges of volatile organic compound–based exhaled breath tests for cancer diagnosis: a systematic review and meta …
Importance The detection and quantification of volatile organic compounds (VOCs) within
exhaled breath have evolved gradually for the diagnosis of cancer. The overall diagnostic …
exhaled breath have evolved gradually for the diagnosis of cancer. The overall diagnostic …
[HTML][HTML] Biosensing chips for cancer diagnosis and treatment: a new wave towards clinical innovation
Recent technological advances in nanoscience and material designing have led to the
development of point-of-care devices for biomolecule sensing and cancer diagnosis. In situ …
development of point-of-care devices for biomolecule sensing and cancer diagnosis. In situ …
[HTML][HTML] Lipid peroxidation produces a diverse mixture of saturated and unsaturated aldehydes in exhaled breath that can serve as biomarkers of lung cancer—a …
The peroxidation of unsaturated fatty acids is a widely recognized metabolic process that
creates a complex mixture of volatile organic compounds including aldehydes. Elevated …
creates a complex mixture of volatile organic compounds including aldehydes. Elevated …
[HTML][HTML] Target analysis of volatile organic compounds in exhaled breath for lung cancer discrimination from other pulmonary diseases and healthy persons
M Koureas, P Kirgou, G Amoutzias… - Metabolites, 2020 - mdpi.com
The aim of the present study was to investigate the ability of breath analysis to distinguish
lung cancer (LC) patients from patients with other respiratory diseases and healthy people …
lung cancer (LC) patients from patients with other respiratory diseases and healthy people …
[HTML][HTML] Monitoring cancer prognosis, diagnosis and treatment efficacy using metabolomics and lipidomics
EG Armitage, AD Southam - Metabolomics, 2016 - Springer
Introduction Cellular metabolism is altered during cancer initiation and progression, which
allows cancer cells to increase anabolic synthesis, avoid apoptosis and adapt to low nutrient …
allows cancer cells to increase anabolic synthesis, avoid apoptosis and adapt to low nutrient …
[HTML][HTML] Early diagnosis of lung cancer using magnetic nanoparticles-integrated systems
Lung cancer (LC) has high morbidity and fatality rate that can be attributed to its poor
diagnostic and monitoring facilities. Hence, there is a need to design advanced detection …
diagnostic and monitoring facilities. Hence, there is a need to design advanced detection …