In vivo adaptive antimicrobial resistance in Klebsiella pneumoniae during antibiotic therapy

S Li, X Feng, M Li, Z Shen - Frontiers in Microbiology, 2023 - frontiersin.org
Klebsiella pneumoniae is one of the leading pathogens contributing to antimicrobial
resistance. The emergence of carbapenem-resistant K. pneumoniae (CRKP) has put the use …

Rationale and evidence for the use of new beta-lactam/beta-lactamase inhibitor combinations and cefiderocol in critically ill patients

F Barbier, S Hraiech, S Kernéis, N Veluppillai… - Annals of Intensive …, 2023 - Springer
Background Healthcare-associated infections involving Gram-negative bacteria (GNB) with
difficult-to-treat resistance (DTR) phenotype are associated with impaired patient-centered …

[HTML][HTML] Acute kidney injury following the concurrent administration of antipseudomonal β-lactams and vancomycin: a network meta-analysis

I Bellos, V Karageorgiou, V Pergialiotis… - Clinical Microbiology and …, 2020 - Elsevier
Background Acute kidney injury is a major complication of vancomycin treatment, especially
when it is co-administered with other nephrotoxins. Objectives This meta-analysis aims to …

Results from the China Antimicrobial Surveillance Network (CHINET) in 2017 of the in vitro activities of ceftazidime-avibactam and ceftolozane-tazobactam against …

D Yin, S Wu, Y Yang, Q Shi, D Dong… - Antimicrobial agents …, 2019 - Am Soc Microbiol
The in vitro activities of ceftazidime-avibactam (CZA), ceftolozane-tazobactam (CT), and
comparators were determined for 1,774 isolates of Enterobacteriaceae and 524 isolates of …

Emergence and Expansion of a Carbapenem-Resistant Pseudomonas aeruginosa Clone Are Associated with Plasmid-Borne blaKPC-2 and Virulence-Related …

Y Hu, C Liu, Q Wang, Y Zeng, Q Sun, L Shu, J Lu… - Msystems, 2021 - Am Soc Microbiol
Pseudomonas aeruginosa is a major opportunistic pathogen and one of the leading
bacterial species causing health care-associated infections. Carbapenems are the most …

Changing epidemiology and decreased mortality associated with carbapenem-resistant gram-negative bacteria, 2000–2017

A Babiker, LG Clarke, M Saul, JA Gealey… - Clinical Infectious …, 2021 - academic.oup.com
Background Carbapenem-resistant gram-negative bacteria (CRGNB) continue to present a
global healthcare crisis. We aimed to identify emerging trends of CRGNB over nearly 2 …

Efficacy of Ceftazidime-Avibactam Versus Polymyxin B and Risk Factors Affecting Clinical Outcomes in Patients With Carbapenem-Resistant Klebsiella pneumoniae …

J Fang, H Li, M Zhang, G Shi, M Liu, Y Wang… - Frontiers in …, 2021 - frontiersin.org
Background: The worldwide outbreak of carbapenem-resistant Klebsiella pneumoniae
(CRKP) has become an urgent public health problem. High mortality and lack of effective …

Clinical characteristics and prognosis of infections caused by OXA-48 carbapenemase-producing Enterobacteriaceae in patients treated with ceftazidime-avibactam

C De la Calle, O Rodríguez, L Morata, F Marco… - International journal of …, 2019 - Elsevier
Background Ceftazidime-avibactam has in vitro activity against Gram-negative bacilli that
produce Class A, C and some D β-lactamases, and has been successfully used in the …

Point prevalence surveys of antimicrobial use: a systematic review and the implications

Z Saleem, MA Hassali, B Godman… - Expert review of anti …, 2020 - Taylor & Francis
Introduction: In view of increasing concerns with antimicrobial resistance (AMR), the World
Health Organization (WHO) instituted a Global Action Plan (GAP) to address this. Area …

Diagnostic stewardship as a team sport: interdisciplinary perspectives on improved implementation of interventions and effect measurement

KD Hueth, AM Prinzi, TT Timbrook - Antibiotics, 2022 - mdpi.com
Diagnostic stewardship aims to deliver the right test to the right patient at the right time and is
optimally combined with antimicrobial stewardship to allow for the right interpretation to …