Revisiting the relationship between essential tremor and Parkinson's disease

R Fekete, J Jankovic - Movement Disorders, 2011 - Wiley Online Library
Background: The relationship between essential tremor and Parkinson's disease has been a
subject of reviews and debates for long time, but there is now growing evidence that the two …

Neuronal activity of the human subthalamic nucleus in the parkinsonian and nonparkinsonian state

F Steigerwald, M Potter, J Herzog… - Journal of …, 2008 - journals.physiology.org
We recorded resting-state neuronal activity from the human subthalamic nucleus (STN)
during functional stereotactic surgeries. By inserting up to five parallel microelectrodes for …

The tremor network targeted by successful VIM deep brain stimulation in humans

JC Klein, MT Barbe, C Seifried, S Baudrexel, M Runge… - Neurology, 2012 - AAN Enterprises
Objective: Deep brain stimulation (DBS) of the ventral intermediate nucleus of thalamus
(VIM) is a treatment option in medically intractable tremor, such as essential tremor or tremor …

BioGraph: unsupervised biomedical knowledge discovery via automated hypothesis generation

AML Liekens, J De Knijf, W Daelemans, B Goethals… - Genome biology, 2011 - Springer
We present BioGraph, a data integration and data mining platform for the exploration and
discovery of biomedical information. The platform offers prioritizations of putative disease …

Diffusion tensor imaging of white matter involvement in essential tremor

JC Klein, B Lorenz, JS Kang, S Baudrexel… - Human brain …, 2011 - Wiley Online Library
This study set out to determine whether there is white matter involvement in essential tremor
(ET), the most common movement disorder. We collected diffusion MRI and analysed …

Parkinsonian rest tremor can be detected accurately based on neuronal oscillations recorded from the subthalamic nucleus

J Hirschmann, JM Schoffelen, A Schnitzler… - Clinical …, 2017 - Elsevier
Objective To investigate the possibility of tremor detection based on deep brain activity.
Methods We re-analyzed recordings of local field potentials (LFPs) from the subthalamic …

LINGO1 variants in essential tremor and Parkinson's disease

H Deng, S Gu, J Jankovic - Acta neurologica scandinavica, 2012 - Wiley Online Library
Deng H, Gu S, Jankovic J. LINGO1 variants in essential tremor and Parkinson's disease.
Acta Neurol Scand: 2012: 125: 1–7© 2011 John Wiley & Sons A/S. The leucine‐rich repeat …

On the origin of tremor in Parkinson's disease

A Dovzhenok, LL Rubchinsky - 2012 - journals.plos.org
The exact origin of tremor in Parkinson's disease remains unknown. We explain why the
existing data converge on the basal ganglia-thalamo-cortical loop as a tremor generator and …

Lingo2 variants associated with essential tremor and Parkinson's disease

YW Wu, KM Prakash, TY Rong, HH Li, Q Xiao, LC Tan… - Human genetics, 2011 - Springer
LINGO2, a member of LRR gene family, has been linked with both Essential tremor (ET) and
Parkinson's disease (PD). However, there is a lack of conclusive evidence regarding the …

Corticomuscular transmission of tremor signals by propriospinal neurons in Parkinson's disease

M Hao, X He, Q Xiao, B Alstermark, N Lan - PloS one, 2013 - journals.plos.org
Cortical oscillatory signals of single and double tremor frequencies act together to cause
tremor in the peripheral limbs of patients with Parkinson's disease (PD). But the corticospinal …