Dear Editor, Cobalamin, also known as vitamin B12, can only be biosynthesized by certain
bacteria and archaea. As an essential nutrient for humans, it should be obtained from daily …

Background Lung adenocarcinoma (LUAD) is the most common subtype of lung cancer,
representing 40% of all cases of this tumor. Despite immense improvements in …

Methylenetetrahydrofolate reductase (MTHFR) deficiency is the most common inherited
disorder of folate metabolism and causes severe hyperhomocysteinaemia. To better …

The present study reports the simultaneous analysis of 26 physiological amino acids in
plasma along with total cysteine and homocysteine by high-performance liquid …

Mutations in CLN3 are a cause of juvenile neuronal ceroid lipofuscinosis (JNCL), also
known as Batten disease. Clinical manifestations include cognitive regression, progressive …

Inherited disorders of B 12 metabolism produce a broad spectrum of manifestations, with
limited knowledge of the influence of age and the function of related genes. We report a …

Mycobacterium tuberculosis is included among a select group of bacteria possessing the
capacity for de novo biosynthesis of vitamin B12, the largest and most complex natural …

Vitamin B12 or cobalamin deficiency is a commonly encountered clinical scenario and most
clinicians will have familiarity prescribing Vitamin B12 to treat their patients. Despite the high …

We previously demonstrated that ABCD4 does not localize to peroxisomes but rather, the
endoplasmic reticulum (ER), because it lacks the NH2-terminal hydrophilic region required …

ATP‐binding cassette (ABC) superfamily is one of the largest groups of primary active
transporters that could be found in all kingdoms of life from bacteria to humans. In humans …