Inhaled corticosteroids in COPD: friend or foe?
The efficacy, safety and positioning of inhaled corticosteroids (ICS) in the treatment of
patients with chronic obstructive pulmonary disease (COPD) is much debated, since it can …
patients with chronic obstructive pulmonary disease (COPD) is much debated, since it can …
Triple therapy versus single and dual long-acting bronchodilator therapy in COPD: a systematic review and meta-analysis
M Cazzola, P Rogliani, L Calzetta… - European Respiratory …, 2018 - Eur Respiratory Soc
We performed a meta-analysis to compare the impact of triple combination therapy with
inhaled corticosteroids (ICS), long-acting β2-agonists (LABAs) and long-acting muscarinic …
inhaled corticosteroids (ICS), long-acting β2-agonists (LABAs) and long-acting muscarinic …
Emulation of randomized clinical trials with nonrandomized database analyses: results of 32 clinical trials
Importance Nonrandomized studies using insurance claims databases can be analyzed to
produce real-world evidence on the effectiveness of medical products. Given the lack of …
produce real-world evidence on the effectiveness of medical products. Given the lack of …
Triple therapy with budesonide/glycopyrrolate/formoterol fumarate with co-suspension delivery technology versus dual therapies in chronic obstructive pulmonary …
GT Ferguson, KF Rabe, FJ Martinez… - The Lancet …, 2018 - thelancet.com
Background Inhaled corticosteroids have been used in patients with chronic obstructive
pulmonary disease (COPD), but the potential benefits of their use in triple therapy are not …
pulmonary disease (COPD), but the potential benefits of their use in triple therapy are not …
Rational use of inhaled corticosteroids for the treatment of COPD
JK Quint, A Ariel, PJ Barnes - npj Primary Care Respiratory Medicine, 2023 - nature.com
Inhaled corticosteroids (ICS) are the mainstay of treatment for asthma, but their role in
chronic obstructive pulmonary disease (COPD) is debated. Recent randomised controlled …
chronic obstructive pulmonary disease (COPD) is debated. Recent randomised controlled …
Comparative effects of LAMA-LABA-ICS vs LAMA-LABA for COPD: cohort study in real-world clinical practice
Background Triple therapy combinations of a long-acting muscarinic antagonist (LAMA), a
long-acting beta 2-agonist (LABA), and an inhaled corticosteroid (ICS) for COPD were …
long-acting beta 2-agonist (LABA), and an inhaled corticosteroid (ICS) for COPD were …
Triple therapy (ICS/LABA/LAMA) in COPD: time for a reappraisal
L Vanfleteren, LM Fabbri, A Papi… - … journal of chronic …, 2018 - Taylor & Francis
Recently, two “fixed triple” single-inhaler combinations of an inhaled corticosteroid (ICS), a
long-acting β2-agonist (LABA), and a long-acting muscarinic antagonist (LAMA) have …
long-acting β2-agonist (LABA), and a long-acting muscarinic antagonist (LAMA) have …
Triple inhaler versus dual bronchodilator therapy in COPD: real-world effectiveness on mortality
Randomized trials of triple therapy including an inhaled corticosteroid (ICS) for chronic
obstructive pulmonary disease (COPD) reported remarkable benefits on mortality compared …
obstructive pulmonary disease (COPD) reported remarkable benefits on mortality compared …
Triple therapy trials in COPD: a precision medicine opportunity
S Suissa, A Ariel - European Respiratory Journal, 2018 - Eur Respiratory Soc
The Global Initiative for Chronic Obstructive Lung Disease (GOLD) strategy document for the
treatment of chronic obstructive pulmonary disease (COPD) suggests that, after …
treatment of chronic obstructive pulmonary disease (COPD) suggests that, after …
Single-inhaler triple versus dual bronchodilator therapy in COPD: real-world comparative effectiveness and safety
Purpose Randomized trials report that single-inhaler triple therapy is more effective than
dual bronchodilators at reducing exacerbations in patients with chronic obstructive …
dual bronchodilators at reducing exacerbations in patients with chronic obstructive …