Gene deregulation in gastric cancer

M Stock, F Otto - Gene, 2005 - Elsevier
Despite its decreasing frequency in the Western world during recent decades, gastric cancer
is still one of the leading causes of cancer-related deaths worldwide. Due to the …

Clinicopathologic and molecular characteristics of gastric cancer showing gastric and intestinal mucin phenotype

N Oue, K Sentani, N Sakamoto, W Yasui - Cancer science, 2015 - Wiley Online Library
Gastric cancer (GC), one of the most common human cancers, can be classified into gastric
or intestinal phenotype according to mucin expression. TP 53 mutation, allelic deletion of the …

Molecular pathology of gastric cancer: research and practice

W Yasui, K Sentani, N Sakamoto, K Anami… - … -Research and Practice, 2011 - Elsevier
Recent advances in the understanding of molecular stomach carcinogenesis are reviewed.
As to molecular events in individual mucin phenotypes of gastric cancer, the CDX2-Reg IV …

Gastric and intestinal phenotypic marker expression in early differentiated-type tumors of the stomach: clinicopathologic significance and genetic background

Y Tajima, K Yamazaki, R Makino, N Nishino… - Clinical Cancer …, 2006 - AACR
Purpose: Gastric and intestinal phenotypic cell markers are expressed in gastric carcinomas,
irrespective of their histologic type. In the present study, we determined the clinicopathologic …

Clinicopathological Analysis of Early‐Stage Gastric Cancers Detected After Successful Eradication of Helicobacter pylori

K Yamamoto, M Kato, M Takahashi, M Haneda… - …, 2011 - Wiley Online Library
Abstract Background and Aims: The results of a randomized controlled study and meta‐
analysis study have recently proved that Helicobacter pylori eradication has a preventive …

Transcriptome dissection of gastric cancer: identification of novel diagnostic and therapeutic targets from pathology specimens

W Yasui, N Oue, K Sentani, N Sakamoto… - Pathology …, 2009 - Wiley Online Library
Gastric cancer is the fourth most common malignancy in the world, and mortality due to
gastric cancer is second only to that from lung cancer.'Transcriptome dissection'is a detailed …

Clinicopathological and prognostic significance of mucin phenotype in gastric cancer

K Wakatsuki, Y Yamada, M Narikiyo… - Journal of surgical …, 2008 - Wiley Online Library
Abstract Background and Objectives Gastric and intestinal mucin phenotype cell markers
are widely expressed in gastric carcinoma cells, irrespective of their tumor histological type …

Quantitative analysis of the effect of Helicobacter pylori on the expressions of SOX2, CDX2, MUC2, MUC5AC, MUC6, TFF1, TFF2, and TFF3 mRNAs in …

K Matsuda, K Yamauchi, T Matsumoto… - Scandinavian journal …, 2008 - Taylor & Francis
Objective. To investigate the phenotypic characters of carcinoma cells and the response of
gastric epithelial cells to Helicobacter pylori (H. pyroli) infection using the gastric carcinoma …

Clinical significance of a papillary adenocarcinoma component in early gastric cancer: a single-center retrospective analysis of 628 surgically resected early gastric …

M Sekiguchi, R Kushima, I Oda, H Suzuki… - Journal of …, 2015 - Springer
Background We recently reported that the presence of a papillary adenocarcinoma (pap)
component was an independent risk factor for lymphatic involvement in endoscopically …

Correlation of Claudin18. 2 expression with clinicopathological characteristics and prognosis in gastric cancer

D Tao, B Guan, Z Li, M Jiao, C Zhou, H Li - Pathology-Research and …, 2023 - Elsevier
Abstract Objectives Claudin18. 2 (Cldn18. 2) is a tight junction protein expressed in gastric
epithelial cells and is an emerging target for gastric cancer (GC). This study aimed to …