The endoplasmic reticulum (ER) is organized in part by adapter proteins that nucleate the
formation of large protein complexes. Tetratricopeptide repeats (TPR) are well studied …

A major hurdle in chemical biology is the delivery of native proteins into the cytosol of
mammalian cells. Herein, we report that esterification of the carboxyl groups of an enzyme …

Folding to a well-defined conformation is essential for the function of structured ribonucleic
acids (RNAs) like the ribosome and tRNA. Structured elements in the untranslated regions …

Sphingolipids are essential components in eukaryotes and have various cellular functions.
Recent developments in genome-editing technologies have facilitated gene disruption in …

Chlamydia trachomatis serovars AC infect conjunctival epithelial cells and untreated
infection can lead to blindness. DK infect genital tract epithelial cells resulting in pelvic …

Transcription-replication interactions occur when DNA replication encounters genomic
regions undergoing transcription. Both replication and transcription are essential for life and …

Despite substantial advances in the treatment of various cancers, many patients still receive
anti-cancer therapies that hardly eradicate tumor cells but inflict considerable side effects. To …

A new therapeutic instrument using ultrasound and a light-emitting diode with an adjustable
optical lens was introduced for suppressing HeLa cell proliferation. A focused-type …

Natural products derived from medicinal plants play increasingly important roles as
alternative antifungal and anticancer agents. The aim of this study was to assess the …

Deciphering a function of a given protein requires investigating various biological aspects.
Usually, the protein of interest is expressed with a fusion tag that aids or allows subsequent …