[HTML][HTML] The PI3K/AKT pathway in obesity and type 2 diabetes
X Huang, G Liu, J Guo, Z Su - International journal of biological …, 2018 - ncbi.nlm.nih.gov
Obesity and type 2 diabetes mellitus are complicated metabolic diseases that affect multiple
organs and are characterized by hyperglycaemia. Currently, stable and effective treatments …
organs and are characterized by hyperglycaemia. Currently, stable and effective treatments …
[HTML][HTML] The potential of mesenchymal stem cells derived from amniotic membrane and amniotic fluid for neuronal regenerative therapy
EY Kim, KB Lee, MK Kim - BMB reports, 2014 - ncbi.nlm.nih.gov
The mesenchymal stem cells (MSCs), which are derived from the mesoderm, are considered
as a readily available source for tissue engineering. They have multipotent differentiation …
as a readily available source for tissue engineering. They have multipotent differentiation …
[HTML][HTML] Fasting-mimicking diet promotes Ngn3-driven β-cell regeneration to reverse diabetes
Stem-cell-based therapies can potentially reverse organ dysfunction and diseases, but the
removal of impaired tissue and activation of a program leading to organ regeneration pose …
removal of impaired tissue and activation of a program leading to organ regeneration pose …
[HTML][HTML] The therapeutic applications of mesenchymal stromal cells from human perinatal tissues in autoimmune diseases
C Yang, M Wu, M You, Y Chen, M Luo… - Stem cell research & …, 2021 - Springer
The autoimmune diseases are characterized by overactivation of immune cells, chronic
inflammation, and immune response to self-antigens, leading to the damage and …
inflammation, and immune response to self-antigens, leading to the damage and …
Characterisation of insulin-producing cells differentiated from tonsil derived mesenchymal stem cells
Abstract Tonsil-derived (T-) mesenchymal stem cells (MSCs) display mutilineage
differentiation potential and self-renewal capacity and have potential as a banking source …
differentiation potential and self-renewal capacity and have potential as a banking source …
[HTML][HTML] Stem cells as a potential therapy in managing various disorders of metabolic syndrome: a systematic review
Recent explorations on mesenchymal stem/stromal cells (MSC) have reported a promising
future for cell-based therapies. MSCs are widely sourced from various tissues and express …
future for cell-based therapies. MSCs are widely sourced from various tissues and express …
[HTML][HTML] The transplantation of Akt-overexpressing amniotic fluid-derived mesenchymal stem cells protects the heart against ischemia-reperfusion injury in rabbits
Y Wang, Y Li, L Song, Y Li… - Molecular Medicine …, 2016 - spandidos-publications.com
Amniotic fluid-derived mesenchymal stem cells (AFMSCs) are an attractive cell source for
applications in regenerative medicine, due to characteristics such as proliferative capacity …
applications in regenerative medicine, due to characteristics such as proliferative capacity …
SOX9+/PTF1A+ cells define the tip progenitor cells of the human fetal pancreas of the second trimester
Significant progress has been made in recent years in characterizing human multipotent
progenitor cells (hMPCs) of the early pancreas; however, the identity and persistence of …
progenitor cells (hMPCs) of the early pancreas; however, the identity and persistence of …
[PDF][PDF] Understanding the bioactivity of stem cells seeded on extracellular matrix scaffolds produced from discarded human kidneys: a critical step towards a new …
Background: In the attempt to develop a clini-cally relevant platform for kidney
bioengineering, we have previously demonstrated that human renal extracellular matrix …
bioengineering, we have previously demonstrated that human renal extracellular matrix …
Pyruvate kinase M1 interacts with A-Raf and inhibits endoplasmic reticulum stress-induced apoptosis by activating MEK1/ERK pathway in mouse insulinoma cells
Apoptotic death of pancreatic β cells is a major cause of type 2 diabetes mellitus (T2D)
progression. Two isoforms of pyruvate kinase, PKM1 and PKM2, have been reported to …
progression. Two isoforms of pyruvate kinase, PKM1 and PKM2, have been reported to …