[HTML][HTML] Follicular lymphoma: a focus on current and emerging therapies

KE Cahill, SM Smith - Oncology (Williston Park, NY), 2022 - ncbi.nlm.nih.gov
Follicular lymphoma (FL) is the most common indolent lymphoma and is characterized by a
relapsing and remitting course. In addition to significant biologic heterogeneity, the clinical …

Follicular lymphoma in the 5th Edition of the WHO-Classification of Haematolymphoid Neoplasms—Updated classification and new biological data

KS Kurz, S Kalmbach, M Ott, AM Staiger, G Ott, H Horn - Cancers, 2023 - mdpi.com
Simple Summary In this paper, we give an overview on the classification of Follicular
lymphoma as modified in the 5th edition of the WHO classification of haematolymphoid …

Epidemiology of diffuse large B-cell lymphoma (DLBCL) and follicular lymphoma (FL) in the United States and Western Europe: population-level projections for 2020 …

G Kanas, W Ge, RGW Quek, K Keeven… - Leukemia & …, 2022 - Taylor & Francis
Diffuse large B-cell lymphoma (DLBCL) and follicular lymphoma (FL) treatments have been
rapidly evolving for patients treated in later lines of therapy (LoT). Country-specific cancer …

Comparative effectiveness of ZUMA-5 (axi-cel) vs SCHOLAR-5 external control in relapsed/refractory follicular lymphoma

P Ghione, ML Palomba, AR Patel… - Blood, The Journal …, 2022 - ashpublications.org
In the pivotal ZUMA-5 trial, axicabtagene ciloleucel (axi-cel; an autologous anti-CD19
chimeric antigen receptor T-cell therapy) demonstrated high rates of durable response in …

Treatment patterns and outcomes of patients with relapsed or refractory follicular lymphoma receiving three or more lines of systemic therapy (LEO CReWE): a …

C Casulo, MC Larson, JJ Lunde… - The Lancet …, 2022 - thelancet.com
Background Novel therapies for relapsed or refractory follicular lymphoma are commonly
evaluated in single-arm studies without formal comparison with other treatments or historical …

Clinical-mediated discovery of pyroptosis in CD8+ T cell and NK cell reveals melanoma heterogeneity by single-cell and bulk sequence

Y Zhang, Y Bai, XX Ma, JK Song, Y Luo, XY Fei… - Cell Death & …, 2023 - nature.com
Histologically, melanoma tissues had fewer positive cells percentage of pyroptosis-related
genes (PRGs), GZMA, GSDMB, NLRP1, IL18, and CHMP4A in epidermal than in normal …

The oral PI3Kδ inhibitor Linperlisib for the treatment of relapsed and/or refractory follicular lymphoma: a phase II, single-arm, open-label clinical trial

T Wang, X Sun, L Qiu, H Su, J Cao, Z Li, Y Song… - Clinical Cancer …, 2023 - AACR
Purpose: To investigate the efficacy and safety of the novel orally active PI3Kδ inhibitor in
relapsed and/or refractory patients with follicular lymphoma (FL) who had received at least …

Novel insights into the pathogenesis of follicular lymphoma by molecular profiling of localized and systemic disease forms

S Kalmbach, M Grau, M Zapukhlyak, E Leich… - Leukemia, 2023 - nature.com
Abstract Knowledge on the pathogenesis of FL is mainly based on data derived from
advanced/systemic stages of FL (sFL) and only small cohorts of localized FL (lFL) have been …

[HTML][HTML] Prospects in the management of patients with follicular lymphoma beyond first-line therapy

D Qualls, G Salles - Haematologica, 2022 - ncbi.nlm.nih.gov
The management of patients with relapsed or refractory follicular lymphoma has evolved
markedly in the last decade, with the availability of new classes of agents (phosphoinositide …

Three-year follow-up analysis of axicabtagene ciloleucel in relapsed/refractory indolent non-Hodgkin lymphoma (ZUMA-5)

SS Neelapu, JC Chavez, AR Sehgal, N Epperla… - Blood, 2024 - ashpublications.org
Axicabtagene ciloleucel (axi-cel) is an autologous anti-CD19 chimeric antigen receptor
(CAR) T-cell therapy approved for relapsed/refractory (R/R) follicular lymphoma (FL) …