Cutaneous wound healing: An update from physiopathology to current therapies

LFS Gushiken, FP Beserra, JK Bastos, CJ Jackson… - Life, 2021 - mdpi.com
The skin is the biggest organ of human body which acts as a protective barrier against
deleterious agents. When this barrier is damaged, the organism promotes the healing …

Mesenchymal stem/stromal cell-derived exosomes for immunomodulatory therapeutics and skin regeneration

DH Ha, H Kim, J Lee, HH Kwon, GH Park, SH Yang… - Cells, 2020 - mdpi.com
Exosomes are nano-sized vesicles that serve as mediators for cell-to-cell communication.
With their unique nucleic acids, proteins, and lipids cargo compositions that reflect the …

Self-powered enzyme-linked microneedle patch for scar-prevention healing of diabetic wounds

X Zhang, Z Wang, H Jiang, H Zeng, N An, B Liu… - Science …, 2023 - science.org
Diabetic wounds with complex pathological features and a difficult-to-heal nature remain a
formidable challenge. To address this challenge, we design and fabricate a self-powered …

Wound healing properties of natural products: mechanisms of action

MS Criollo-Mendoza, LA Contreras-Angulo… - Molecules, 2023 - mdpi.com
A wound is the loss of the normal integrity, structure, and functions of the skin due to a
physical, chemical, or mechanical agent. Wound repair consists of an orderly and complex …

The complexity of the post-burn immune response: an overview of the associated local and systemic complications

HI Korkmaz, G Flokstra, M Waasdorp, A Pijpe… - Cells, 2023 - mdpi.com
Burn injury induces a complex inflammatory response, both locally and systemically, and is
not yet completely unravelled and understood. In order to enable the development of …

Gel/hydrogel‐based in situ biomaterial platforms for cancer postoperative treatment and recovery

Y Feng, Z Zhang, W Tang, Y Dai - Exploration, 2023 - Wiley Online Library
Tumor surgical resection is the major strategy for cancer treatment. Meanwhile,
perioperative treatment especially the postoperative adjuvant anticancer strategies play …

Wound healing and microbiome, an unexpected relationship

L Canchy, D Kerob, AL Demessant… - Journal of the …, 2023 - Wiley Online Library
Skin wounds are common and represent a major public health and economical problem,
with risks of complications and a significant negative impact on the quality of life of patients …

The role of extracellular matrix in skin wound healing

NN Potekaev, OB Borzykh, GV Medvedev… - Journal of Clinical …, 2021 - mdpi.com
Impaired wound healing is one of the unsolved problems of modern medicine, affecting
patients' quality of life and causing serious economic losses. Impaired wound healing can …

The insights of microbes' roles in wound healing: A comprehensive review

T Maheswary, AA Nurul, MB Fauzi - Pharmaceutics, 2021 - mdpi.com
A diverse range of normal flora populates the human skin and numbers are relatively
different between individuals and parts of the skin. Humans and normal flora have formed a …

Beta‐caryophyllene as an antioxidant, anti‐inflammatory and re‐epithelialization activities in a rat skin wound excision model

LFS Gushiken, FP Beserra, MF Hussni… - Oxidative medicine …, 2022 - Wiley Online Library
The skin is a critical organ for the maintenance of the integrity and protection of the
organism. When a wound occurs, a sequence of healing mechanisms is triggered to …