Complete Rescue of HTLV-1p12KO Infectivity by Depletion of Monocytes Together with NK and CD8+ T Cells

A Gutowska, S Sarkis, MA Rahman, KC Goldfarbmuren… - Pathogens, 2024 - mdpi.com
The transient depletion of monocytes alone prior to exposure of macaques to HTLV-1
enhances both HTLV-1WT (wild type) and HTLV-1p12KO (Orf-1 knockout) infectivity, but …

HTLV-1 Proliferation after CD8+ Cell Depletion by Monoclonal Anti-CD8 Antibody Administration in Latently HTLV-1-Infected Cynomolgus Macaques

M Nakamura-Hoshi, T Nomura, M Nishizawa… - Microbiology …, 2023 - Am Soc Microbiol
HTLV-1 can cause serious diseases such as adult T-cell leukemia (ATL) in humans after
chronic asymptomatic latent infection with substantial proviral load. Proviruses are …