Migraine headache has high incidence, frequent attacks, and stubbornness accompanied
with increased vascular pulsation. Its incidence is higher in women than in men …

The release of the neuropeptide of calcitonin gene-related peptide (CGRP) plays a key role
in the mechanisms of migraine pathology and pain perception as it causes vasodilatation …

Migraine is the most common disabling primary headache globally. Attacks often present
with unilateral throbbing headache and an array of associated symptoms, including, nausea …

Calcitonin gene-related peptide (CGRP) is a 37 amino-acid neuropeptide that initiates
intracellular signalling through binding and activation of a group of calcitonin-family class …

The heart is imbued with a vast lymphatic network which is responsible for fluid homeostasis
and immune cell trafficking. Disturbances in the forces that regulate microvascular fluid …

原发性头痛是高致残率的疾病之一, 往往于青壮年时期发病, 患者在承受痛苦的同时也给社会带
来沉重的疾病负担, 然而其发病机制尚不明确. 切实可靠的原发性头痛动物模型的建立有助于 …