Ever since the initial discovery of the system, damage to the nigrostriatal dopamine system
has been associated with motor impairments, akinesia in animals and Parkinson's disease …

Positron emission tomography (PET) is a useful technique for the consecutive investigation
of the relationship between changes in neurotransmission biomarkers and behavioral signs …

Monkeys treated with 1-methyl-4-phenyl-1, 2, 5, 6-tetrahydropyridine (MPTP) are currently
the best animal model for Parkinson's disease (PD) and have been widely used for …

The mechanisms of action of high‐frequency stimulation (HFS) of the subthalamic nucleus
(STN) remain only partially understood. Hitherto, experimental studies have suggested that …

Abstract Background Non-human primate Parkinson's disease (PD) models are essential for
PD research. The most extensively used PD monkey models are induced with 1-methyl-4 …

Electrically evoked compound action potentials (ECAPs) generated in the subthalamic
nucleus (STN) contain features that may be useful for titrating deep brain stimulation (DBS) …

Background Gastrointestinal (GI) and metabolic function are frequently altered in
Parkinson's disease (PD). Although enteric nervous system anatomopathological alterations …

US20040209810A1 - Method of treating Parkinson's disease in humans by intraputaminal
infusion of glial cell-line derived neurotrophic factor - Google Patents US20040209810A1 …

In spite of the current availability of several pharmacological therapies for the treatment of
Parkinson's disease, side effects are invariably manifested during long-term treatment …

Background. Autologous neural cell ecosystem (ANCE) transplantation improves motor
recovery in MPTP monkeys. These motor symptoms were assessed using semi-quantitative …