Parkinson's disease (PD) is a progressive neurodegenerative disorder. An experimental
model of this disease is produced in nonhuman primates by the administration of the …

Dopamine active transporter (DAT) single photon emission computerised tomography
(SPECT) is considered a useful and practical technique for early diagnosis of Parkinson's …

The MPTP monkey model of Parkinson's disease (PD) has allowed huge advances
regarding the understanding of the pathological mechanisms of PD and l-DOPA-induced …

Identification of genetic and physiological mechanisms underlying a drug's or mutation's
effects on motor performance could be aided by the existence of a simple observation-based …

Parkinson's disease (PD) is a neurodegenerative disease characterized by muscular
trembling palsy due to lack of dopamine (DA) in the substantia nigra-striatum (nigrostriatal) …

Dopamine is thought to directly influence the neurophysiological mechanisms of both
performance monitoring and cognitive control—two processes that are critically linked in the …

Clinical diagnosis of Parkinson's disease (PD) is characterized by the classical features of
tremor, bradykinesia and rigidity, which are present only when more than 70%-80 …

Parkinson's disease (PD) is characterized by motor symptoms, usually accompanied by
cognitive deficits. The question addressed in this study is whether complexity of routine …

The lack of evidence indicating the accumulation of phosphorylated α-synuclein (P-α-syn), a
neuropathological hallmark of Parkinson disease (PD), limits the application of 6-OHDA …

Presymptomatic diagnosis of the loss of nigrostriatal neurons that characterises Parkinson's
disease, is a crucial issue for future neuroprotective therapies as degeneration exceeds 70 …