mRNA translation decodes nucleotide into amino acid sequences. However, translation has
also been shown to affect mRNA stability depending on codon composition in model …

Transfer RNA is heavily modified and plays a central role in protein synthesis and cellular
functions. Here we demonstrate that ALKBH3 is a 1-methyladenosine (m1A) and 3 …

Despite its biological importance, tRNA has not been adequately sequenced by standard
methods because of its abundant post-transcriptional modifications and stable structure …

Deep analysis of next-generation sequencing data unveils numerous small non-coding
RNAs with distinct functions. Recently, fragments derived from tRNA, named as tRNA …

Messenger RNA (mRNA) stability and translational efficiency are two crucial aspects of the
post-transcriptional process that profoundly impact protein production in a cell. While it is …

Specific, regulated modification of RNAs is important for proper gene expression,. tRNAs are
rich with various chemical modifications that affect their stability and function,. 7 …

Messenger RNA (mRNA) translation by the ribosome represents the final step of a
complicated molecular dance from DNA to protein. Although classically considered a …

Summary tRNA is the most extensively modified RNA in cells. On average, a bacterial tRNA
contains 8 modifications per molecule and a eukaryotic tRNA contains 13 modifications per …

N 6-methyladenosine (m6A) is the most prevalent and internal modification that occurs in the
messenger RNAs (mRNA) of most eukaryotes, although its functional relevance remained a …

Transfer RNA (tRNA)-derived small RNAs (tsRNAs), a novel category of small noncoding
RNAs, are enzymatically cleaved from tRNAs. Previous reports have shed some light on the …