Seizing the fate of lymph nodes in immunotherapy: To preserve or not?

ZY Xu, ZZ Li, LM Cao, NN Zhong, XH Liu, GR Wang… - Cancer Letters, 2024 - Elsevier
Lymph node dissection has been a long-standing diagnostic and therapeutic strategy for
metastatic cancers. However, questions over myriad related complications and survival …

Lymph Node-on-Chip Technology: Cutting-Edge Advances in Immune Microenvironment Simulation

Q Wang, Y Yang, Z Chen, B Li, Y Niu, X Li - Pharmaceutics, 2024 - mdpi.com
Organ-on-a-chip technology is attracting growing interest across various domains as a
crucial platform for drug screening and testing and is set to play a significant role in precision …

Porphyrin-Based Self-Assembled Nanoparticles for PET/MR Imaging of Sentinel Lymph Node Metastasis

X Fu, Z Cai, S Fu, H Cai, M Li, H Gu, R Jin… - … Applied Materials & …, 2024 - ACS Publications
Diagnosing of lymph node metastasis is challenging sometimes, and multimodal imaging
offers a promising method to improve the accuracy. This work developed porphyrin-based …

[HTML][HTML] Improved pharmacokinetic and lymphatic uptake of Rose Bengal after transfersome intradermal deposition using hollow microneedles

S Demartis, G Rassu, QK Anjani… - Journal of Controlled …, 2024 - Elsevier
The lymphatic system is active in several processes that regulate human diseases, among
which cancer progression stands out. Thus, various drug delivery systems have been …

Setting-up a training programme for intraoperative molecular imaging and sentinel node mapping: how to teach? How to learn?

RA Valdés Olmos, A Collarino, DDD Rietbergen… - European Journal of …, 2023 - Springer
Background The current expansion of image-guided surgery is closely related to the role
played by radio-guided surgery in supporting the sentinel node (SN) procedure during more …

Comparative aspects of targeted sentinel lymph node mapping in veterinary and human medicine: opportunities for future research

ML Oblak, HY Lu, AS Ram, C McKenna - Frontiers in Medicine, 2024 - frontiersin.org
There is a significant overlap in the genetic, metabolic and epigenetic alterations between
human and companion animal cancers, including those of the oral cavity, breast, bladder …

SPDYC serves as a prognostic biomarker related to lipid metabolism and the immune microenvironment in breast cancer

X Chen, H Peng, Z Zhang, C Yang, Y Liu, Y Chen… - Immunologic …, 2024 - Springer
Breast cancer remains the most common malignant carcinoma among women globally and
is resistant to several therapeutic agents. There is a need for novel targets to improve the …

[HTML][HTML] Diagnostic value of one-step nucleic acid amplification for sentinel lymph node metastasis in cytokeratin 19-positive tumors: evidence from bioinformatics and …

K Li, M Meng, W Zhang, J Li, Y Wang… - Frontiers in …, 2024 - ncbi.nlm.nih.gov
Background The status of the sentinel lymph nodes (SLNs) was an important prognostic
factor in varies cancers. A one-step nucleic acid amplification (OSNA) assay, a molecular …

[HTML][HTML] ENO2 promotes anoikis resistance in anaplastic thyroid cancer by maintaining redox homeostasis

Y Zhang, X Ji, Y Wang - Gland Surgery, 2024 - ncbi.nlm.nih.gov
Background Anoikis presents a significant barrier in the metastasis of cancer. As the most
aggressive type of thyroid cancer, anaplastic thyroid cancer (ATC) exhibits a high risk of …

HLA class II polymorphisms as prognostic biomarkers for right and left-sided colon cancer

A Attia, A Lagha, A Mezlini… - The International …, 2024 - journals.sagepub.com
Background Colon cancer (CC) is one of the most common malignancies worldwide.
Characterization of new prognostic biomarkers for right-sided CC (RCC) and left-sided CC …