The hypothalamic-pituitary system is considered to be a seminal event that emerged prior to
or during the differentiation of the ancestral agnathans (jawless vertebrates). Hagfishes as …

The goal of this study was to identify whether Pacific hagfish (Eptatretus stoutii) possess
glucocorticoid and mineralocorticoid responses and to examine the potential role (s) of four …

Environmental stressors, gonadal degenerative diseases and tumour development can
significantly alter the oocyte physiology, and species fertility and fitness. To expand the …

One or more distinct forms of the nuclear estrogen receptor (ER) have been isolated from
many vertebrates to date. To better understand the molecular evolution of ERs, we cloned …

Since hagfishes are considered the most primitive vertebrate known, extant or extinct,
studies on their reproduction are indispensable for understanding phylogenetic aspects of …

Corticosteroids are synthesized from cholesterol by steroidogenic enzyme catalysts
belonging to two main families: the cytochrome p450s (CYPs) and hydroxysteroid …

Abstract The Pacific hagfish, Eptatretus stoutii, is a basal, jawless marine fish considered key
to understanding the evolution of vertebrates as is their sister group, the lampreys …

Reproduction in gnathostomes (jawed vertebrates) is controlled by a hierarchically
organized endocrine system called the hypothalamic-pituitary-gonadal axis. In spite of the …