RNA modifications have become hot topics recently. By influencing RNA processes,
including generation, transportation, function, and metabolization, they act as critical …

Autoimmune diseases (AIDs) are immune disorders whose incidence and prevalence are
increasing year by year. AIDs are produced by the immune system's misidentification of self …

Inflammatory dermatosis is characterized by persistent inflammatory infiltration and hard
repair of diseased skin. As a member of the human innate immune cells, macrophages …

Background Osteoarthritis (OA) is a common joint disorder worldwide which causes great
health and economic burden. However, there remains an unmet goal to develop an effective …

Malaria is one of the major global health concerns that affect millions of people worldwide
annually, especially people residing in the developing countries. The previously …

Rheumatoid arthritis (RA) is a destructive inflammatory autoimmune disease that causes
pain and disability. Many of the currently available drugs for treating RA patients are aimed …

Integrins are transmembrane receptors that possess distinct ligand-binding specificities in
the extracellular domain and signaling properties in the cytoplasmic domain. While most …

Artemisinin is a natural bioactive sesquiterpene lactone containing an unusual
endoperoxide 1, 2, 4-trioxane ring. It is derived from the herbal medicinal plant Artemisia …

Artemisinin (Art) is a natural sesquiterpene lactone that is claimed to exhibit various
bioactivities. The poor solubility of Art in both water and oil hinders its application in …

In situ-activated therapy is a decent option for localized diseases with improved efficacies
and reduced side effects, which is heavily dependent on the local conversion or activation of …