A review on the green synthesis of benzimidazole derivatives and their pharmacological activities

M Nardi, NCH Cano, S Simeonov, R Bence, A Kurutos… - Catalysts, 2023 - mdpi.com
Benzimidazoles and their derivatives play an extraordinarily significant role as therapeutic
agents, eg, antiulcer, analgesic, and anthelmintic drugs. The organic synthesis of …

Alternative assisted extraction methods of phenolic compounds using NaDESs

M Coscarella, M Nardi, K Alipieva, S Bonacci… - Antioxidants, 2023 - mdpi.com
A renewed understanding of eco-friendly principles is moving the industrial sector toward a
shift in the utilization of less harmful solvents as a main strategy to improve manufacturing …

Montmorillonite K10: An efficient organo-heterogeneous catalyst for synthesis of benzimidazole derivatives

S Bonacci, G Iriti, S Mancuso, P Novelli, R Paonessa… - Catalysts, 2020 - mdpi.com
The use of toxic solvents, high energy consumption, the production of waste and the
application of traditional processes that do not follow the principles of green chemistry are …

Recycling of Epoxy Resins with Degradable Structures or Dynamic Cross-Linking Networks: A Review

Y Li, Y Wu, K Li, H Lin, M Wang, L Zheng… - Industrial & …, 2024 - ACS Publications
Traditional epoxy resins (EPR), represented by bisphenol A type, have high chemical bond
energy, low polarity, and stable chemical properties. The topological structure after curing …

Synthesis and antioxidant evaluation of lipophilic oleuropein aglycone derivatives

M Nardi, S Bonacci, L Cariati, P Costanzo, M Oliverio… - Food & function, 2017 - pubs.rsc.org
Oleuropein is the most important phenolic compound present in olive cultivars, but it is
scarcely present in extra virgin olive oil (EVOO) due to its high hydrophilicity and …

Erbium(III) Chloride in Ethyl Lactate as a Smart Ecofriendly System for Efficient and Rapid Stereoselective Synthesis of trans-4,5-Diaminocyclopent-2-enones

A Procopio, P Costanzo, M Curini, M Nardi… - ACS Sustainable …, 2013 - ACS Publications
Erbium (III) chloride in ethyl lactate is used as an environmentally very friendly system for the
reaction of furfural and amines to yield diastereoselectively differently N, N-substituted trans …

Aqueous MW eco-friendly protocol for amino group protection

M Nardi, NH Cano, P Costanzo, M Oliverio… - RSC Advances, 2015 - pubs.rsc.org
In this paper a new catalyst-free and on-water method for protection of amines and amino
acids with di-tert-butyl dicarbonate, 9-fluorenylmethoxycarbonyl chloride, acetyl chloride and …

Montmorillonite K10-catalyzed solvent-free conversion of furfural into cyclopentenones

S Bonacci, M Nardi, P Costanzo, A De Nino… - Catalysts, 2019 - mdpi.com
A simple and eco-friendly montmorillonite K10 (MK10)-catalyzed method for the synthesis of
cyclopentenone derivatives from biomass-produced furfural has been developed. The …

Asymmetric Cycloaddition of β,γ‐Unsaturated α‐Ketoesters with Electron‐Rich Alkenes Catalyzed by a Chiral Er(OTf)3/N,N′‐Dioxide Complex: Highly Enantioselective …

Y Zhu, M Xie, S Dong, X Zhao, L Lin… - … –A European Journal, 2011 - Wiley Online Library
The asymmetric inverse‐electron‐demand hetero‐Diels–Alder (HDA) reactions of β, γ‐
unsaturated α‐ketoesters with electron‐rich alkenes were investigated, with an N, N …

Lipophilic hydroxytyrosol esters: fatty acid conjugates for potential topical administration

A Procopio, C Celia, M Nardi, M Oliverio… - Journal of natural …, 2011 - ACS Publications
Hydroxytyrosol is a potent antioxidant natural molecule isolated from olive leaves and fruits.
The presence of three hydroxy groups in its structure poses a limit for the topical application …