[HTML][HTML] The Caenorhabditis elegans cuticle and precuticle: a model for studying dynamic apical extracellular matrices in vivo
MV Sundaram, N Pujol - Genetics, 2024 - academic.oup.com
Apical extracellular matrices (aECMs) coat the exposed surfaces of animal bodies to shape
tissues, influence social interactions, and protect against pathogens and other …
tissues, influence social interactions, and protect against pathogens and other …
Progress and challenges in the use of blood biomarkers in relapsing polychondritis
Y Liu, X Li, L Cheng, H Zhan, Y Huang… - Clinical and …, 2023 - academic.oup.com
Relapsing polychondritis (RP) is a rare inflammatory disease with significant individual
heterogeneity that involves systemic organs. The diagnosis of RP mainly depends on the …
heterogeneity that involves systemic organs. The diagnosis of RP mainly depends on the …
Basic components of connective tissues and extracellular matrix: fibronectin, fibrinogen, laminin, elastin, fibrillins, fibulins, matrilins, tenascins and thrombospondins
J Halper - Progress in heritable soft connective tissue diseases, 2021 - Springer
Collagens are the most abundant components of the extracellular matrix (ECM) and many
types of soft tissues. Elastin is another major component of certain soft tissues, such as …
types of soft tissues. Elastin is another major component of certain soft tissues, such as …
[HTML][HTML] Mitochondrial respiratory chain function promotes extracellular matrix integrity in cartilage
K Bubb, T Holzer, JL Nolte, M Krüger, R Wilson… - Journal of Biological …, 2021 - ASBMB
Energy metabolism and extracellular matrix (ECM) function together orchestrate and
maintain tissue organization, but crosstalk between these processes is poorly understood …
maintain tissue organization, but crosstalk between these processes is poorly understood …
[HTML][HTML] Matrilin-3 supports neuroprotection in ischemic stroke by suppressing astrocyte-mediated neuroinflammation
X Zhou, Y Zhu, D Gao, M Li, L Lin, Z Wang, H Du, Y Xu… - Cell Reports, 2024 - cell.com
In the brain, the role of matrilin-3, an extracellular matrix component in cartilage, is unknown.
Here, we identify that matrilin-3 decreased in reactive astrocytes but was unchanged in …
Here, we identify that matrilin-3 decreased in reactive astrocytes but was unchanged in …
[HTML][HTML] Mice lacking the matrilin family of extracellular matrix proteins develop mild skeletal abnormalities and are susceptible to age-associated osteoarthritis
P Li, L Fleischhauer, C Nicolae, C Prein… - International journal of …, 2020 - mdpi.com
Matrilins (MATN1, MATN2, MATN3 and MATN4) are adaptor proteins of the cartilage
extracellular matrix (ECM), which bridge the collagen II and proteoglycan networks. In …
extracellular matrix (ECM), which bridge the collagen II and proteoglycan networks. In …
Autoimmunity and autoinflammation: relapsing polychondritis and VEXAS syndrome challenge
Relapsing polychondritis is a chronic autoimmune inflammatory condition characterized by
recurrent episodes of inflammation at the level of cartilaginous structures and tissues rich in …
recurrent episodes of inflammation at the level of cartilaginous structures and tissues rich in …
[HTML][HTML] Structural and biophysical analysis of the CLCA1 VWA domain suggests mode of TMEM16A engagement
KN Berry, TJ Brett - Cell reports, 2020 - cell.com
The secreted protein calcium-activated chloride channel regulator 1 (CLCA1) utilizes a von
Willebrand factor type A (VWA) domain to bind to and potentiate the calcium-activated …
Willebrand factor type A (VWA) domain to bind to and potentiate the calcium-activated …
[HTML][HTML] Mesenchymal Stem Cell-Derived Exosomes as a Treatment Option for Osteoarthritis
A Vadhan, T Gupta, WL Hsu - International Journal of Molecular Sciences, 2024 - mdpi.com
Osteoarthritis (OA) is a leading cause of pain and disability worldwide in elderly people.
There is a critical need to develop novel therapeutic strategies that can effectively manage …
There is a critical need to develop novel therapeutic strategies that can effectively manage …
The roles of extracellular matrix molecules matrilins and aggrecan in bone development and articular cartilage functions
P Li - 2020 - edoc.ub.uni-muenchen.de
Bones are important constituents of the organ systems of the vertebrates providing body
support, physical protection for inner organs, movement facilitation, mineral storage and a …
support, physical protection for inner organs, movement facilitation, mineral storage and a …