[HTML][HTML] Therapeutic strategies of three-dimensional stem cell spheroids and organoids for tissue repair and regeneration

W Kim, Y Gwon, S Park, H Kim, J Kim - Bioactive Materials, 2023 - Elsevier
Abstract Three-dimensional (3D) stem cell culture systems have attracted considerable
attention as a way to better mimic the complex interactions between individual cells and the …

[HTML][HTML] Cell–scaffold interactions in tissue engineering for oral and craniofacial reconstruction

F Wang, X Cai, Y Shen, L Meng - Bioactive Materials, 2023 - Elsevier
Tissue engineering (TE) is critical in oral and craniofacial reconstruction. One of the most
popular topics on the biomaterial-based tissue regeneration process may be the interaction …

Young exosome bio‐nanoparticles restore aging‐impaired tendon stem/progenitor cell function and reparative capacity

S Jin, Y Wang, X Wu, Z Li, L Zhu, Y Niu… - Advanced …, 2023 - Wiley Online Library
Aging impairs tendon stem/progenitor cell function and tendon homeostasis, however,
effective treatments for aging‐induced tendon diseases are lacking. Exosomes are naturally …

Rejuvenation of tendon stem/progenitor cells for functional tendon regeneration through platelet-derived exosomes loaded with recombinant Yap1

J Lu, X Yang, C He, Y Chen, C Li, S Li, Y Chen, Y Wu… - Acta Biomaterialia, 2023 - Elsevier
The regenerative capabilities including self-renewal, migration and differentiation potentials
shift from the embryonic phase to the mature period of endogenous tendon stem/progenitor …

Mechanically robust hydrogels facilitating bone regeneration through epigenetic modulation

T Yu, L Zhang, X Dou, R Bai, H Wang, J Deng… - Advanced …, 2022 - Wiley Online Library
Abstract Development of artificial biomaterials by mimicking extracellular matrix of bone
tissue is a promising strategy for bone regeneration. Hydrogel has emerged as a type of …

Energy‐supporting enzyme‐mimic nanoscaffold facilitates tendon regeneration based on a mitochondrial protection and microenvironment remodeling strategy

S Wang, Z Yao, X Zhang, J Li, C Huang… - Advanced …, 2022 - Wiley Online Library
Tendon injury is a tricky and prevalent motor system disease, leading to compromised daily
activity and disability. Insufficient regenerative capability and dysregulation of immune …

A biomaterial‐based hedging immune strategy for Scarless tendon healing

Z Wang, L Xiang, F Lin, Y Tang, L Deng… - Advanced …, 2022 - Wiley Online Library
Scarring rather than regeneration, is an inevitable outcome of unbalanced amplifications of
inflammation‐destructive signals and atresia of the regenerative niche. However, identifying …

[HTML][HTML] A hierarchical bilayer architecture for complex tissue regeneration

M Yu, D Luo, J Qiao, J Guo, D He, S Jin, L Tang… - Bioactive materials, 2022 - Elsevier
Engineering a complete, physiologically functional, periodontal complex structure remains a
great clinical challenge due to the highly hierarchical architecture of the periodontium and …

[HTML][HTML] Deep learning-predicted dihydroartemisinin rescues osteoporosis by maintaining mesenchymal stem cell stemness through activating histone 3 Lys 9 …

R Wang, Y Wang, Y Niu, D He, S Jin, Z Li… - ACS Central …, 2023 - ACS Publications
Maintaining the stemness of bone marrow mesenchymal stem cells (BMMSCs) is crucial for
bone homeostasis and regeneration. However, in vitro expansion and bone diseases impair …

Mechanically Robust Hemostatic Hydrogel Membranes with Programmable Strain-Adaptive Microdomain Entanglement for Wound Treatment in Dynamic Tissues

L Tan, C Huyan, Y Wang, M Li, D Liu, M Liu, Z Luo… - ACS …, 2024 - ACS Publications
Supramolecular hydrogels emerge as a promising paradigm for sutureless wound
management. However, their translation is still challenged by the insufficient mechanical …