Visible‐light‐photocatalyzed methods employed in synthetic transformations present
attractive properties such as environmentally friendly, safety, availability and excellent …

The delivery of a drug to a specific organ or tissue at an efficacious concentration is the
pharmacokinetic (PK) hallmark of promoting effective pharmacological action at a target site …

Malaria is a global infectious disease that remains a leading cause of morbidity and mortality
in the developing world. Multiple environmental and host and parasite factors govern the …

Initiatives to eradicate malaria have a good impact on P. falciparum malaria worldwide. P.
vivax, however, still presents significant difficulties. This is due to its unique biological traits …

Host-directed therapy (HDT) is gaining traction as a strategy to combat infectious diseases
caused by viruses and intracellular bacteria, but its implementation in the context of parasitic …

Background Artemether–lumefantrine is widely used for uncomplicated Plasmodium
falciparum malaria; sulfadoxine–pyrimethamine plus amodiaquine is used for seasonal …

An 11-step, 8-pot synthesis of the antimalarial drug tafenoquine succinate was achieved in
42% overall yield using commercially available starting materials. Compared to the previous …

Chemotherapy plays a key role in breast cancer therapy, but drug resistance and unwanted
side effects make the treatment less effective. We propose a new combination model that …

Although malaria remains a big burden to many countries that it threatens their socio-
economic stability, particularly in the countries where malaria is endemic, there have been …

The pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
has severely affected human lives around the world as well as the global economy …