Abstract Introduction and Aims. Alcohol is an established risk factor for liver cirrhosis. It
remains unclear, however, whether this relationship follows a continuous dose–response …

This review discusses the inconsistent recommendations on alcohol consumption and its
association with chronic disease, highlighting the need for an evidence-based consensus …

Most people who are regular consumers of psychoactive drugs are not drug addicts, nor will
they ever become addicts. In neurobiological theories, non-addictive drug consumption is …

Based on their pharmacological properties, psychoactive drugs are supposed to take control
of the natural reward system to finally drive compulsory drug seeking and consumption …

Gastrointestinal physiology is dynamic and complex at the best of times, and a multitude of
known variables can affect the overall bioavailability of drugs delivered via the oral route …

Psychoactive drugs with addiction potential are widely used by people of virtually all cultures
in a non-addictive way. In order to understand this behaviour, its population penetrance, and …

Alcohol consumption in the older adult is of major concern with the advent of baby boomers
coming into the over 65-age bracket. Alcohol consumption has been touted as beneficial for …

These guidelines were commissioned by Health Canada as part of an international initiative
to develop sound methodologies and approaches for estimating the socioeconomic …

Alcohol has been linked to a considerable burden of disease worldwide. Recent
epidemiological research has shown that dimensions of alcohol exposure other than …

Alcohol has a direct impact on the digestive system due to its contact with mucosal lining
and interference with digestive functions. Various diseases of the gastrointestinal tract …