Over a decade of schizophrenia research using human induced pluripotent stem cell (iPSC)-
derived neural models has provided substantial data describing neurobiological …

Psychiatry has a well-established tradition of comparing drug-induced experiences to
psychotic symptoms, based on shared phenomena such as altered perceptions. The present …

The thalamic connectivity system, with the thalamus as the central node, enables
transmission of the brain's neural computations via extensive connections to cortical …

Psychosis spectrum disorder (PSD) affects 1% of the world population and results in a
lifetime of chronic disability, causing devastating personal and economic consequences …

Thalamocortical dysfunction is thought to underlie the pathophysiology of chronic pain
revealed by electroencephalographic studies. The thalamus serves as a primary relay …

Flicker light stimulation (FLS) uses stroboscopic light on closed eyes to induce transient
visual hallucinatory phenomena, such as the perception of geometric patterns, motion, and …

A shared mechanism across species heralds the arrival of self-generated sensations,
helping the brain to anticipate, and therefore distinguish, self-generated from externally …

Background Dysfunctional cognitive control processes are now well understood to be core
features of schizophrenia (SZ). A body of work suggests that the dorsolateral prefrontal …

Schizophrenia (SZ) is a severe psychiatric disorder, with a prevalence of 1–2% world-wide
and substantial health-and social care costs. The pathology is influenced by both genetic …

Background Accurate psychiatric risk assessment requires biomarkers that are both stable
and adaptable to development. Functional network connectivity (FNC), which steadily …