Fbxw7 is a driver of uterine carcinosarcoma by promoting epithelial-mesenchymal transition
Uterine carcinosarcoma is an aggressive variant of endometrial carcinoma characterized by
unusual histologic features including discrete malignant epithelial and mesenchymal …
unusual histologic features including discrete malignant epithelial and mesenchymal …
Genome-wide array CGH analysis of murine neuroblastoma reveals distinct genomic aberrations which parallel those in human tumors
CS Hackett, JG Hodgson, ME Law, J Fridlyand… - Cancer research, 2003 - AACR
Neuroblastoma, the third most common tumor of childhood, is a complex disease in which
few genetic mutations have been identified. Mice expressing a human MYCN oncogene …
few genetic mutations have been identified. Mice expressing a human MYCN oncogene …
ProNGF, a cytokine induced after myocardial infarction in humans, targets pericytes to promote microvascular damage and activation
CJ Siao, CU Lorentz, P Kermani, T Marinic… - Journal of Experimental …, 2012 - rupress.org
Treatment of acute cardiac ischemia focuses on reestablishment of blood flow in coronary
arteries. However, impaired microvascular perfusion damages peri-infarct tissue, despite …
arteries. However, impaired microvascular perfusion damages peri-infarct tissue, despite …
Development of five digits is controlled by a bipartite long-range cis-regulator
LA Lettice, I Williamson, PS Devenney… - …, 2014 - journals.biologists.com
Conservation within intergenic DNA often highlights regulatory elements that control gene
expression from a long range. How conservation within a single element relates to …
expression from a long range. How conservation within a single element relates to …
Loss of Ca2+/calmodulin kinase kinase β affects the formation of some, but not all, types of hippocampus-dependent long-term memory
Long-term memory (LTM) requires activation of the transcription factor cAMP-responsive
element binding protein (CREB). Signaling by the Ca2+/calmodulin (CaM) kinase cascade …
element binding protein (CREB). Signaling by the Ca2+/calmodulin (CaM) kinase cascade …
Vitamin D and the RNA transcriptome: more than mRNA regulation
MJ Campbell - Frontiers in Physiology, 2014 - frontiersin.org
The GRCh37. p13 primary assembly of the human genome contains 20805 protein coding
mRNA, and 37147 non-protein coding genes and pseudogenes that as a result of RNA …
mRNA, and 37147 non-protein coding genes and pseudogenes that as a result of RNA …
Role of the Transcriptional Corepressor Bcor in Embryonic Stem Cell Differentiation and Early Embryonic Development
JA Wamstad, CM Corcoran, AM Keating, VJ Bardwell - PloS one, 2008 - journals.plos.org
Bcor (BCL6 corepressor) is a widely expressed gene that is mutated in patients with X-linked
Oculofaciocardiodental (OFCD) syndrome. BCOR regulates gene expression in association …
Oculofaciocardiodental (OFCD) syndrome. BCOR regulates gene expression in association …
Organic anion and cation transporters occur in pairs of similar and similarly expressed genes
SA Eraly, BA Hamilton, SK Nigam - Biochemical and biophysical research …, 2003 - Elsevier
Organic anion and cation transporters (OATs, OCTs, OCTNs, and ORCTLs), transmembrane
proteins essential to renal xenobiotic excretion, are encoded by a group of related genes. As …
proteins essential to renal xenobiotic excretion, are encoded by a group of related genes. As …
A double-deletion mutation in the Pitx3 gene causes arrested lens development in aphakia mice
DK Rieger, E Reichenberger, W McLean, A Sidow… - Genomics, 2001 - Elsevier
The recessive aphakia (ak) mouse mutant is characterized by bilateral microphthalmia due
to a failure of lens morphogenesis. We fine-mapped the ak locus to the interval between …
to a failure of lens morphogenesis. We fine-mapped the ak locus to the interval between …
Insights from human/mouse genome comparisons
LA Pennacchio - Mammalian genome, 2003 - Springer
Large-scale public genomic sequencing efforts have provided a wealth of vertebrate
sequence data poised to provide insights into mammalian biology. These include deep …
sequence data poised to provide insights into mammalian biology. These include deep …