Adaptive immune cell dysregulation and role in acute pancreatitis disease progression and treatment

P Fonteh, M Smith, M Brand - Archivum immunologiae et therapiae …, 2018 - Springer
Acute pancreatitis (AP) is an inflammation of the pancreas caused by various stimuli
including excessive alcohol consumption, gallstone disease and certain viral infections …

Controlled trial of high-dose octreotide in treatment of acute pancreatitis: evidence of improvement in disease severity

N Beechey-Newman - Digestive diseases and sciences, 1993 - Springer
Nineteen consecutive patients with acute pancreatitis were sequentially allocated to
treatment with high-dose octreotide (N= 9) or to act as controls (N= 10). All other aspects of …

Alcohol and the pancreas

S Sehenker, R Montalvo - Recent Developments in Alcoholism: The …, 1998 - Springer
Alcoholic pancreatitis may be one of the most serious adverse consequences of alcohol
abuse. Its diagnosis, as it has for many years, depends primarily on clinical acumen in …

Octreotide treatment in patients with necrotizing pancreatitis and pulmonary failure

F Fiedler, G Jauernig, V Keim, A Richter… - Intensive care …, 1996 - Springer
Objective To determine the efficiency of intravenous infusion of octreotide in the treatment of
patients with severe pancreatitis and pulmonary failure. Design Prospective, case-control …

Aprotinin in severe acute pancreatitis

M Smith, HM Kocher, BJ Hunt - International journal of clinical …, 2010 - Wiley Online Library
Aprotinin, a Kunitz protease inhibitor, has a wide inhibitory action with particular activity
against trypsin, chymotrypsin and kallikrein, making it theoretically attractive in ameliorating …

A double-blinded multicenter trial of somatostatin in the treatment of acute pancreatitis.

I Gjørup, O Roikjaer, B Andersen… - Surgery, gynecology …, 1992 - europepmc.org
To evaluate the effect of somatostatin in the treatment of acute pancreatitis, 63 patients were
randomly allocated to continuous intravenous infusion for three days of 250 micrograms of …

Experimental models of acute pancreatitis and their relevance to human disease

DW Rattner - Scandinavian journal of gastroenterology, 1996 - Taylor & Francis
There are no experimental models which mimic the most common causes of human acute
pancreatitis, ie gallstones and alcohol abuse. However, existing models can reproduce the …

Effect of iron depletion in patients with nonalcoholic fatty liver disease without carbohydrate intolerance

L Valenti, AL Fracanzani, S Fargion - Gastroenterology, 2003 - Elsevier
Dear Sir: We read with interest Dr. Facchini's paper on the relationship among fasting and
glucose stimulated insulin concentration, insulin resistance, and iron depletion in patients …

Gallstone pancreatitis

MG Patti, CA Pellegrini - Surgical Clinics of North America, 1990 - Elsevier
Gallstone pancreatitis is caused by the transient blockage of the ampulla of Vater by a
migrating gallstone. The obstruction causes extracellular or intracellular activation of …

Protective effect of antithrombin III in acute experimental pancreatitis in rats

WK Bleeker, J Agterberg, G Rigter, CE Hack… - Digestive diseases and …, 1992 - Springer
In the present study we investigated the therapeutic action of antithrombin III (AT III) in
taurocholate-induced experimental pancreatitis with high lethality in rats. High-dose AT III …