Bacterial defences: mechanisms, evolution and antimicrobial resistance

WPJ Smith, BR Wucher, CD Nadell… - Nature Reviews …, 2023 - nature.com
Throughout their evolutionary history, bacteria have faced diverse threats from other
microorganisms, including competing bacteria, bacteriophages and predators. In response …

Mobile genetic element flexibility as an underlying principle to bacterial evolution

AJ Weisberg, JH Chang - Annual Review of Microbiology, 2023 - annualreviews.org
Mobile genetic elements are key to the evolution of bacteria and traits that affect host and
ecosystem health. Here, we use a framework of a hierarchical and modular system that …

Emergence and spread of antibiotic-resistant foodborne pathogens from farm to table

J Kim, J Ahn - Food Science and Biotechnology, 2022 - Springer
Antibiotics have been overused and misused for preventive and therapeutic purposes.
Specifically, antibiotics are frequently used as growth promoters for improving productivity …

Threats of antibiotic resistance: an obliged reappraisal

F Baquero - International Microbiology, 2021 - Springer
We are living in a society of fear, where the objectivity in estimating risks is distorted by the
media and the interested parties. During more than half of a century, the feeling of antibiotic …

Integrons in the development of antimicrobial resistance: critical review and perspectives

BA Bhat, RA Mir, H Qadri, R Dhiman… - Frontiers in …, 2023 - frontiersin.org
Antibiotic resistance development and pathogen cross-dissemination are both considered
essential risks to human health on a worldwide scale. Antimicrobial resistance genes …

The natural history of integrons

TM Ghaly, MR Gillings, A Penesyan, Q Qi, V Rajabal… - Microorganisms, 2021 - mdpi.com
Integrons were first identified because of their central role in assembling and disseminating
antibiotic resistance genes in commensal and pathogenic bacteria. However, these clinically …

Within-patient evolution of plasmid-mediated antimicrobial resistance

J DelaFuente, L Toribio-Celestino… - Nature ecology & …, 2022 - nature.com
Antimicrobial resistance (AMR) in bacteria is a major threat to public health; one of the key
elements in the spread and evolution of AMR in clinical pathogens is the transfer of …

Profile and resistance levels of 136 integron resistance genes

A Hipólito, L García-Pastor, E Vergara, T Jové… - npj Antimicrobials and …, 2023 - nature.com
Integrons have played a major role in the rise and spread of multidrug resistance in Gram-
negative pathogens and are nowadays commonplace among clinical isolates. These …

A South African Perspective on the Microbiological and Chemical Quality of Meat: Plausible Public Health Implications

CE Manyi-Loh, R Lues - Microorganisms, 2023 - mdpi.com
Meat comprises proteins, fats, vitamins, and trace elements, essential nutrients for the
growth and development of the body. The increased demand for meat necessitates the use …

Unbridled integrons: a matter of host factors

E Richard, B Darracq, C Loot, D Mazel - Cells, 2022 - mdpi.com
Integrons are powerful recombination systems found in bacteria, which act as platforms
capable of capturing, stockpiling, excising and reordering mobile elements called cassettes …