Curcumin, a constituent of the spice turmeric, has been shown to reduce the adenoma
burden in rodent models of colorectal cancer accompanied by a reduction of levels of the …

Abstract Overexpression of Cyclooxygenase‐2 (COX‐2) is observed in most tumor types.
Increased COX‐2 activity and synthesis of prostaglandins stimulates proliferation …

OBJECTIVES: Use of non-steroidal anti-inflammatory drugs (NSAIDs) has been inversely
associated with colorectal cancer; however, the association within colorectal subsites or …

A 4-stage colon simulator and a cell culture-based human intestinal epithelial function
model were combined to study the effects of a soluble fiber, polydextrose (PDX), on …

Background Mantle cell lymphoma (MCL) is an incurable B cell lymphoma and accounts for
6% of all non-Hodgkin's lymphomas. On the genetic level, MCL is characterized by the …

Objective Non-steroidal anti-inflammatory drug (NSAID) use decreases both the incidence of
colorectal cancer and recurrence of adenomas among patients with prior colorectal …

Cyclooxygenases (Cox)-1 and-2 play important roles in gastrointestinal health; chronic
overexpression of Cox-2 is associated with inflammatory and cancerous disease, whereas …

Adlay (Coix lachryma-jobi L. var. ma-yuen Stapf) is a grass crop used in traditional Chinese
medicine and as a nutritious food. It has been reported that adlay has anti-inflammatory and …

Background: Previous epidemiologic studies have shown that regular use of nonsteroidal
anti-inflammatory drugs (NSAIDs) is associated with decreased colorectal cancer risk …

Eicosanoids, including prostaglandins (PGs) and thromboxanes, are broadly bioactive lipid
mediators and increase colon tumorigenesis possibly through chronic inflammatory …