[HTML][HTML] S-nitrosylated and non-nitrosylated COX2 have differential expression and distinct subcellular localization in normal and breast cancer tissue

S Jindal, ND Pennock, A Klug, J Narasimhan… - NPJ Breast …, 2020 - nature.com
Immunohistochemical (IHC) staining in breast cancer shows both gain and loss of COX2
expression with disease risk and progression. We investigated four common COX2 antibody …

Quantitative, tissue-specific analysis of cyclooxygenase gene expression in the pathogenesis of Barrett's adenocarcinoma

H Kuramochi, D Vallböhmer, K Uchida… - Journal of …, 2004 - Springer
Abstract Cyclooxygenase (Cox-2) is implicated in the pathogenesis of many cancers
including esophageal adenocarcinoma (EAC), whereas the role of the isoform Cox-1 in …

[HTML][HTML] Pre-diagnostic NSAID use but not hormone therapy is associated with improved colorectal cancer survival in women

AE Coghill, PA Newcomb, VM Chia, Y Zheng… - British journal of …, 2011 - nature.com
Background: Non-steroidal anti-inflammatory drugs (NSAIDs) and hormone therapy (HT)
independently decrease the risk of colorectal cancer. However, their role in altering survival …

Association of nonsteroidal anti-inflammatory drugs with colorectal cancer by subgroups in the vitamins and lifestyle (VITAL) study

X Wang, U Peters, JD Potter, E White - Cancer Epidemiology, Biomarkers & …, 2015 - AACR
Background: There is substantial evidence that use of NSAIDs reduces the risk of colorectal
cancer, but no subgroup has been identified for which the chemoprevention effect outweighs …

Phytochemical Investigations of Three Rhodocodon (Hyacinthaceae Sensu APG II) Species

S Schwikkard, A Alqahtani, W Knirsch… - Journal of Natural …, 2017 - ACS Publications
The genus Rhodocodon (Hyacinthaceae sensu APG II) is endemic to Madagascar, and its
phytochemistry has not been described previously. The phytochemistry of three species in …

Intron 1 retaining cyclooxygenase 1 splice variant is induced by osmotic stress in human intestinal epithelial cells

JT Nurmi, PA Puolakkainen, NE Rautonen - … , leukotrienes and essential …, 2005 - Elsevier
The biological roles of intron 1 retaining cyclooxygenase (Cox) 1 splice variants Cox-3 and
PCox-1a (Cox-1ir) are not known. In humans, Cox-3 transcription has previously been …

Oxylipin patterns in human colon adenomas

C Schmöcker, H Gottschall, KM Rund, L Kutzner… - … and Essential Fatty …, 2021 - Elsevier
Objective Cyclooxygenase (COX)-derived prostaglandin E 2 (PGE 2) is an important lipid
mediator in colorectal carcinoma (CRC) pathogenesis. Other lipid mediators derived from …

Decreased polyunsaturated fatty acid content contributes to increased survival in human colon cancer

M Oraldi, A Trombetta, F Biasi, RA Canuto… - Journal of …, 2009 - Wiley Online Library
Among diet components, some fatty acids are known to affect several stages of colon
carcinogenesis, whereas others are probably helpful in preventing tumors. In light of this, our …

No effect of exercise on colon mucosal prostaglandin concentrations: a 12-month randomized controlled trial

PE Abrahamson, IB King, CM Ulrich, RE Rudolph… - … Biomarkers & Prevention, 2007 - AACR
Background: Epidemiologic studies provide evidence that exercise is associated with
reduced risk of colon cancer. Exercise may exert protective effects on the colon by …

COX-2 expression in pseudomyxoma peritonei

Z Gatalica, B Loggie - Cancer letters, 2006 - Elsevier
COX-2 expression was studied using an immunohistochemical method in 75 patients with
pseudomyxoma peritonei (PMP). Twenty-five patients presented with disseminated …