Here we investigate the effect of S-dipalmitoylation on the electron capture dissociation
(ECD) behavior of peptides. The ECD and collision induced dissociation (CID) of peptides …

Peptide radicals play a significant role in biology as well as mass spectrometry. They can be
differentiated into two groups: conventional hydrogen-deficient radicals, eg M+• as in …

The biochemical processes responsible for proper cellular operation are wholly dependent
on interactions between biomolecules constructed with canonical yet alterable structures …

Conventional tandem mass spectrometry relies on even-electron fragmentation that
provides limited structural information for glycerophospholipids (GP), which are key …

Electron capture dissociation (ECD) was first reported in 1998 by Zubarev, Kelleher, and
McLafferty. 1 ECD produces odd-electron ions by the recombination of a low-energy …

Mass spectrometry is a powerful technique for molecular characterization. Although the
mass of intact ions is often revealing, most experiments employ further activation to generate …

The dynamic S-palmitoylation regulates many intracellular events, including protein
trafficking, anchoring, targeting, and protein-protein interactions. Direct detection of S …

Dit werk is mede mogelijk gemaakt door financiering van de Nederlandse Organisatie voor
Wetenschappelijk Onderzoek (NWO), Chemische Wetenschappen, middels VICI-project nr …

Gas-phase collisions of Gly and Ala with free electrons were employed to form positive ions
at well determined energies. At elevated molecular vapor pressure, protonated [Gly+ H]+ …

Protein radicals play important roles in biological systems including their involvement in
enzyme catalytic sites, aging, neurodegenerative diseases, and oxidative damage to …