Computational psychiatry: from synapses to sentience

K Friston - Molecular psychiatry, 2023 - nature.com
This review considers computational psychiatry from a particular viewpoint: namely, a
commitment to explaining psychopathology in terms of pathophysiology. It rests on the …

Questions and controversies in the study of time-varying functional connectivity in resting fMRI

DJ Lurie, D Kessler, DS Bassett, RF Betzel… - Network …, 2020 - direct.mit.edu
The brain is a complex, multiscale dynamical system composed of many interacting regions.
Knowledge of the spatiotemporal organization of these interactions is critical for establishing …

[HTML][HTML] Active inference on discrete state-spaces: A synthesis

L Da Costa, T Parr, N Sajid, S Veselic, V Neacsu… - Journal of Mathematical …, 2020 - Elsevier
Active inference is a normative principle underwriting perception, action, planning, decision-
making and learning in biological or artificial agents. From its inception, its associated …

New directions in predictive processing

J Hohwy - Mind & Language, 2020 - Wiley Online Library
Predictive processing (PP) is now a prominent theoretical framework in the philosophy of
mind and cognitive science. This review focuses on PP research with a relatively …

Path integrals, particular kinds, and strange things

K Friston, L Da Costa, DAR Sakthivadivel, C Heins… - Physics of Life …, 2023 - Elsevier
This paper describes a path integral formulation of the free energy principle. The ensuing
account expresses the paths or trajectories that a particle takes as it evolves over time. The …

[HTML][HTML] Why brain criticality is clinically relevant: a scoping review

V Zimmern - Frontiers in neural circuits, 2020 - frontiersin.org
The past twenty-five years have seen a strong increase in the number of publications related
to criticality in different areas of neuroscience. The potential of criticality to explain various …

Generalised free energy and active inference

T Parr, KJ Friston - Biological cybernetics, 2019 - Springer
Active inference is an approach to understanding behaviour that rests upon the idea that the
brain uses an internal generative model to predict incoming sensory data. The fit between …

The free energy principle for perception and action: A deep learning perspective

P Mazzaglia, T Verbelen, O Catal, B Dhoedt - Entropy, 2022 - mdpi.com
The free energy principle, and its corollary active inference, constitute a bio-inspired theory
that assumes biological agents act to remain in a restricted set of preferred states of the …

Composite pain biomarker signatures for objective assessment and effective treatment

I Tracey, CJ Woolf, NA Andrews - Neuron, 2019 - cell.com
Pain is a subjective sensory experience that can, mostly, be reported but cannot be directly
measured or quantified. Nevertheless, a suite of biomarkers related to mechanisms, neural …

The anatomy of inference: generative models and brain structure

T Parr, KJ Friston - Frontiers in computational neuroscience, 2018 - frontiersin.org
To infer the causes of its sensations, the brain must call on a generative (predictive) model.
This necessitates passing local messages between populations of neurons to update beliefs …