Lactation is critical to infant short-term and long-term health and protects mothers from
breast cancer, ovarian cancer and type 2 diabetes mellitus. The mammary gland is a …

The mammary gland (MG) is an exocrine gland present in female mammals responsible for
the production and secretion of milk during the process of lactation. It is mainly composed by …

Osteoarthritis (OA), the leading cause of pain and disability worldwide, disproportionally
affects individuals with obesity. The mechanisms by which obesity leads to the onset and …

Abstract The goal of Working Group 1 in the Breastmilk Ecology: Genesis of Infant Nutrition
(BEGIN) Project was to outline factors influencing biological processes governing human …

Adipose tissue secretes numerous cytokines (termed 'adipokines') that have known or
hypothesized actions on skeletal muscle. The majority of adipokines have been implicated …

Bone marrow adipocytes accumulate with age and in diverse disease states. However, their
origins and adaptations in these conditions remain unclear, impairing our understanding of …

Due to their endocrine disruption properties, phthalate plasticizers such as di (2-ethylhexyl)
phthalate (DEHP) can affect the hormone-dependent development of the mammary gland …

Obesity is a modern pandemic with negative consequences in women's reproductive health.
Women with overweight and obesity can develop mammary gland alterations that unable …

Adult stem cell niche is a special environment composed of a variety stromal cells and
signals, which cooperatively regulate tissue development and homeostasis. It is of great …

Mammary gland (MG) undergoes critical points of structural changes throughout a woman's
life. During the perinatal and pubertal stages, MG develops through growth and …