[HTML][HTML] Mesenchymal Stem Cell-Derived Exosomes as a Treatment Option for Osteoarthritis

A Vadhan, T Gupta, WL Hsu - International Journal of Molecular Sciences, 2024 - mdpi.com
Osteoarthritis (OA) is a leading cause of pain and disability worldwide in elderly people.
There is a critical need to develop novel therapeutic strategies that can effectively manage …

Catabolic mediators from TLR2-mediated proteoglycan aggrecan peptide-stimulated chondrocytes are reduced by Lactobacillus-conditioned media

P Sengprasert, P Waitayangkoon, O Kamenkit… - Scientific Reports, 2024 - nature.com
In osteoarthritis (OA), extracellular matrix (ECM) digestion by cartilage-degrading enzymes
drives cartilage destruction and generates ECM fragments, such as proteoglycan aggrecan …

Causal associations between circulating immune cells and osteoarthritis: A bidirectional mendelian randomization study

C Xu, S Wang, X Chen, T Zhang, Z Ni, G Ji… - International …, 2024 - Elsevier
Purpose Osteoarthritis (OA) is a common degenerative joint disease, with its etiology
remaining poorly understood. Our study aims to explore the causal associations between …

Effectiveness of Bacillus genus application in the treatment of osteoarthritis by bioactive fish concentrate

DG Rekalov, IO Daniuk, RL Kulinych… - PAIN, JOINTS …, 2024 - pjs.zaslavsky.com.ua
Background. Understanding the impact of gut microbiota on the development of
osteoarthritis (OA) and investigating the potential of probiotics as a treatment remain crucial …

[PDF][PDF] Ефективність поєднаного застосування пробіотика на основі бактерій роду Bacillus із біоактивним концентратом морської риби в лікуванні …

К РЛ - Bol Sustavy Pozvonochnik, 2024 - pjs.zaslavsky.com.ua
Актуальність. Актуальним залишається вивчення впливу мікробіоти кишечника на
патогенетичні ланки розвитку остеоартриту (ОА), а також дослідження ефективності …

HPExplainPro: A Framework for Pan-cancer Prognosis Prediction Based on Deep Interpretable Learning

G Houwu, Z Huang, M Jin - Artificial Intelligence and Data Science for … - openreview.net
Prognostic prediction research holds immense significance in guiding doctors in evaluating
the effectiveness of various treatment modalities, thereby facilitating the selection of the most …

In vivo myndgreining á Smo próteini í brjóskfrumum

EL Taylor - skemman.is
Við virkjun á hedgehog (Hh) boðferlinum ferðast Smoothened (Smo) próteinið inn í
frumbifhár frumunnar þar sem samskipti við aðra þætti Hh boðferilsins leiða til umritunar á …