Introduction Cytokine adsorption using the CytoSorb® adsorber has been proposed in
various clinical settings including sepsis, ARDS, hyperinflammatory syndromes, cardiac …

Vasoplegic syndrome (VS) is a common complication following cardiovascular surgery with
cardiopulmonary bypass (CPB), and its incidence varies from 5 to 44%. It is defined as a …

Critically ill patients with sepsis and severe COVID-19 are commonly characterized by a
dysregulated immune response and an acute kidney injury. Continuous renal replacement …

Both high mobility group box-1 (HMGB1) and histones are major damage-associated
molecular patterns (DAPMs) that mediate lethal systemic inflammation, activation of the …

OBJECTIVES: The effectiveness of CytoSorb at removing inflammatory mediators in critically
ill patients is controversial. DATA SOURCES: Electronic databases were searched from …

Endotoxin, also referred to as lipopolysaccharide (LPS), is a potent stimulator of the
inflammatory cascade which may progress to sepsis and septic shock. The term endotoxic …

Extracorporeal hemoperfusion (EHP) may improve the course and outcomes of patients with
septic shock by targeting cytokines or bacterial endotoxins (lipopolysaccharide [LPS]). Here …

The development of new extracorporeal blood purification (EBP) techniques has led to
increased application in clinical practice but also inconsistencies in nomenclature and …

Adsorbents, which can be used to directly eliminate uremic toxins from blood, are decisive
for hemoperfusion that maintains human renal function. However, developing adsorbents …

Sepsis is a leading cause of disability and mortality worldwide. The pathophysiology of
sepsis relies on the maladaptive host response to pathogens that fosters unbalanced organ …