Alveologenesis is a spatially coordinated morphogenetic event, during which alveolar
myofibroblasts surround the terminal sacs constructed by epithelial cells and endothelial …

The mechanical properties of solid tumors influence tumor cell phenotype and the ability to
invade surrounding tissues. Using bioengineered scaffolds to provide a matrix …

Renal cell carcinoma (RCC) is characterized by substantial vasculatures and increased fluid
movement in tumor microenvironment, and the fluid shear stress modulates malignance …

Abstract 3D printing enables the customized design of implant structures for accurately
regulating host responses. However, polysaccharides, as a major biomaterial category with …

The Hippo pathway regulates and contributes to several hallmarks of prostate cancer (PCa).
Although the elucidation of YAP function in PCa is in its infancy, emerging studies have shed …

Tensile stress is one of the most common mechanical stresses on the connective tissues of
human organs. Cell stretching devices have been developed to study the effects of tensile …

In brief Trophectoderm is the first tissue to differentiate in the early mammalian embryo and
is essential for hatching, implantation, and placentation. This review article discusses the …

The pathogenesis of posterior longitudinal ligament ossification (OPLL) remains
inadequately understood. Mechanical stimulation is one of the important pathogenic factors …

Fibroblasts are the main producers of extracellular matrix (ECM) responsible for ECM
maintenance and repair, a process often disrupted in chronic lung diseases. The …

Skeletal stem and progenitor cells (SSPCs) are the multi-potent, self-renewing cell lineages
that form the hematopoietic environment and adventitial structures of the skeletal tissues …