The phosphatidylinositol 3-kinase (PI3K)/AKT/mammalian target of rapamycin (mTOR)
pathway is activated in the majority of human cancers. This pathway is known to play a key …

Elevated rates of reactive oxygen species (ROS) have been detected in almost all cancers,
where they promote many aspects of tumour development and progression. However …

The human body consists of countless cells with the possibility of excessive and
uncontrolled proliferation under certain dysregulated circumstances that could cause …

ABSTRACT C-Myc overexpression is a common finding in pancreatic cancer and predicts
the aggressive behavior of cancer cells. It binds to the promoter of different genes, thereby …

Diabetic retinopathy (DR) is a microvascular complication of diabetes and one of the most
common causes of blindness in active stage. This study is performed to explore the effects of …

Objective: This study explored the ability of microRNA-135a (miR-135a) to influence cell
proliferation, migration, invasion, apoptosis and tumor angiogenesis through the IGF …

After an ischemic injury, the heart undergoes a complex process of structural and functional
remodeling that involves several steps, including inflammatory and fibrotic responses. In this …

Despite the significant decline in mortality, cardiovascular diseases are still the leading
cause of death worldwide. Among them, myocardial infarction (MI) seems to be the most …

Background Human placenta-derived mesenchymal stem cell (hPMSC) transplantation has
been demonstrated to be an effective way of recovering ovarian function in mice with …

In recent years, the incidence of colorectal cancer (CRC) has increased and research into
new treatment methods for CRC has become a hot topic. Naringin has an inhibitory effect on …